Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report

被引：0

作者：

Yang, Xue-Jiao ^{[1
]}

Wu, Yong-Juan ^{[2
]}

Wang, Jing-Zhong ^{[2
]}

Zheng, Yu-Lan ^{[1
]}

Li, Xiao-Qi ^{[2
]}

机构：

[1] Hubei Univ Arts & Sci, Affiliated Hosp, Xiangyang Cent Hosp, Dept Resp & Crit Care Med, Xiangyang, Peoples R China

[2] Hubei Univ Arts & Sci, Xiangyang Cent Hosp, Affiliated Hosp, Dept Intervent Radiol, Xiangyang, Peoples R China

来源：

FRONTIERS IN MEDICINE | 2025年 / 12卷

关键词：

lung squamous cell carcinoma; massive hemoptysis; pulmonary artery pseudoaneurysm; tislelizumab; tumor necrosis;

D O I：

10.3389/fmed.2025.1524248

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lung squamous cell carcinoma (SCC) is a subtype of non-small cell lung cancer with high incidence and mortality rates. While chemotherapy and immune checkpoint inhibitors (ICIs) have become crucial treatment options for SCC, these may be associated with unforeseen complications. Here, we present a 65-year-old male of hemoptysis caused by a pulmonary artery pseudoaneurysm (PAP) after chemotherapy combined with tislelizumab for lung SCC. After confirmation with angiography, successful embolization was performed to occlude the pseudoaneurysm and proximal artery. To our knowledge, this is the first reported case of PAP formation after chemotherapy combined with tislelizumab for lung SCC.

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