Palladium-Catalyzed Asymmetric C-H Activation for the Synthesis of Planar Chiral Ferrocene Sulfonamides

被引：0

作者：

Zhang, Chaowei ^{[1
]}

Xu, Bingbin ^{[1
]}

Liu, Wenlong ^{[1
]}

Zhao, Jing ^{[1
]}

Duan, Weiliang ^{[1
,2
]}

机构：

[1] Yangzhou Univ, Coll Chem & Chem Engn, Yangzhou 225002, Jiangsu, Peoples R China

[2] Inner Mongolia Univ, Coll Chem & Chem Engn, Hohhot 010000, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2025年 / 45卷 / 02期

基金：

中国国家自然科学基金;

关键词：

palladium catalysis; plane chirality; ferrocene; sulfonamide; C-H bond activation; ENANTIOSELECTIVE SYNTHESIS; STEREOSELECTIVE SYNTHESES; ORTHO-LITHIATION; SULFANILAMIDE; SILYLATION; ARYLATION; LIGANDS; REDOX; ENTRY;

D O I：

10.6023/cjoc202404002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pd-catalyzed asymmetric synthesis of planar chiral ferrocenes by enantioselective intramolecular C-H arylation of N-(2-bromoaryl)-N-alkylferrocenesulfonamide were efficiently achieved in good enantioselectivities (up to 90% ee) and high yields.

引用

页码：707 / 716

页数：10

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