Disease characteristics and monitoring of IDH1/IDH2-mutated acute myeloid leukemia

被引：0

作者：

Dantec, Melinda ^{[1
,2
]}

Dufosse, Maxime ^{[3
]}

Boudry, Augustin ^{[1
,4
]}

Fournier, Elise ^{[1
,2
]}

Goursaud, Laure ^{[2
,3
]}

Lebon, Delphine ^{[5
,6
]}

Bories, Claire ^{[7
]}

Plantier, Isabelle ^{[8
]}

Tricot, Sabine ^{[9
]}

Daniel, Adrien ^{[10
]}

Willaume, Alexandre ^{[11
]}

Coiteux, Valerie ^{[3
]}

Berthon, Celine ^{[2
,3
]}

Marolleau, Jean-Pierre ^{[5
,6
]}

Preudhomme, Claude ^{[1
,2
]}

Duployez, Nicolas ^{[1
,2
]}

Fenwarth, Laurene ^{[1
,2
]}

机构：

[1] CHU Lille, Biol & Pathol Ctr, Lab Hematol, Lille, France

[2] Univ Lille, U1277 Canther, INSERM, Lille, France

[3] CHU Lille, Claude Huriez Hosp, Dept Hematol, Lille, France

[4] Univ Lille, ULR 2694 Metr, Lille, France

[5] CHU Amiens, Dept Hematol & Cell Therapy, Amiens, France

[6] Univ Picardie Jules Verne, EA4666 HEMATIM, Amiens, France

[7] CH Lens, Dept Hematol, Lens, France

[8] CH Roubaix, Dept Hematol, Roubaix, France

[9] CH Valenciennes, Dept Hematol, Valenciennes, France

[10] CH Dunkerque, Dept Hematol, Dunkerque, France

[11] St Vincent de Paul Hosp, Dept Hematol, Lille, France

来源：

BLOOD CANCER JOURNAL | 2025年 / 15卷 / 01期

关键词：

PROGNOSTIC-SIGNIFICANCE; RESIDUAL DISEASE; MUTATIONS; RELEVANCE;

D O I：

10.1038/s41408-025-01304-x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[graphic not available: see fulltext]

引用

页数：4

共 15 条

[1] Impact of IDH1 and IDH2 mutation detection at diagnosis and in remission in patients with AML receiving allogeneic transplantation [J].

Bill, Marius ;

Jentzsch, Madlen ;

Bischof, Lara ;

Kohlschmidt, Jessica ;

Grimm, Juliane ;

Schmalbrock, Laura Katharina ;

Backhaus, Donata ;

Brauer, Dominic ;

Goldmann, Karoline ;

Franke, Georg -Nikolaus ;

Vucinic, Vladan ;

Niederwieser, Dietger ;

Mims, Alice S. ;

Platzbecker, Uwe ;

Eisfeld, Ann-Kathrin ;

Schwind, Sebastian .

BLOOD ADVANCES, 2023, 7 (03) :436-444

[2] DNA Sequencing to Detect Residual Disease in Adults With Acute Myeloid Leukemia Prior to Hematopoietic Cell Transplant [J].

Dillon, Laura W. ;

Gui, Gege ;

Page, Kristin M. ;

Ravindra, Niveditha ;

Wong, Zoe C. ;

Andrew, Georgia ;

Mukherjee, Devdeep ;

Zeger, Scott L. ;

El Chaer, Firas ;

Spellman, Stephen ;

Howard, Alan ;

Chen, Karen ;

Auletta, Jeffery ;

Devine, Steven M. ;

Jimenez, Antonio Martin Jimenez ;

De Lima, Marcos J. G. ;

Litzow, Mark R. ;

Kebriaei, Partow ;

Saber, Wael ;

Weisdorf, Daniel J. ;

Hourigan, Christopher S. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2023, 329 (09) :745-755

[3] Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML [J].

DiNardo, Courtney D. ;

Ravandi, Farhad ;

Agresta, Sam ;

Konopleva, Marina ;

Takahashi, Koichi ;

Kadia, Tapan ;

Routbort, Mark ;

Patel, Keyur P. ;

Brandt, Mark ;

Pierce, Sherry ;

Garcia-Manero, Guillermo ;

Cortes, Jorge ;

Kantarjian, Hagop .

AMERICAN JOURNAL OF HEMATOLOGY, 2015, 90 (08) :732-736

[4] Clinical relevance of IDH1/2 mutant allele burden during follow-up in acute myeloid leukemia. A study by the French ALFA group [J].

Ferret, Yann ;

Boissel, Nicolas ;

Helevaut, Nathalie ;

Madic, Jordan ;

Nibourel, Olivier ;

Marceau-Renaut, Alice ;

Bucci, Maxime ;

Geffroy, Sandrine ;

Celli-Lebras, Karine ;

Castaigne, Sylvie ;

Thomas, Xavier ;

Terre, Christine ;

Dombret, Herve ;

Preudhomme, Claude ;

Renneville, Aline .

HAEMATOLOGICA, 2018, 103 (05) :822-829

[5] Venetoclax and hypomethylating agent combination therapy in newly diagnosed acute myeloid leukemia: Genotype signatures for response and survival among 301 consecutive patients [J].

Gangat, Naseema ;

Karrar, Omer ;

Iftikhar, Moazah ;

Mccullough, Kristen ;

Johnson, Isla M. ;

Abdelmagid, Maymona ;

Abdallah, Mostafa ;

Al-Kali, Aref ;

Alkhateeb, Hassan B. ;

Begna, Kebede H. ;

Mangaonkar, Abhishek ;

Saliba, Antoine N. ;

Torghabeh, Mehrdad Hefazi ;

Litzow, Mark R. ;

Hogan, William ;

Shah, Mithun ;

Patnaik, Mrinal M. ;

Pardanani, Animesh ;

Badar, Talha ;

Murthy, Hemant ;

Foran, James ;

Palmer, Jeanne ;

Sproat, Lisa ;

Khera, Nandita ;

Yi, Cecilia Arana ;

Tefferi, Ayalew .

AMERICAN JOURNAL OF HEMATOLOGY, 2024, 99 (02) :193-202

[6] The prognostic significance of IDH2 mutations in AML depends on the location of the mutation [J].

Green, Claire L. ;

Evans, Catherine M. ;

Zhao, Lu ;

Hills, Robert K. ;

Burnett, Alan K. ;

Linch, David C. ;

Gale, Rosemary E. .

BLOOD, 2011, 118 (02) :409-412

[7] The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status [J].

Green, Claire L. ;

Evans, Catherine M. ;

Hills, Robert K. ;

Burnett, Alan K. ;

Linch, David C. ;

Gale, Rosemary E. .

BLOOD, 2010, 116 (15) :2779-2782

[8]

Gui GG, 2025, BONE MARROW TRANSPL, V60, P154, DOI 10.1038/s41409-024-02447-4

[9] Measurable residual mutated IDH2 before allogeneic transplant for acute myeloid leukemia [J].

Gui, Gege ;

Ravindra, Niveditha ;

Hegde, Pranay S. ;

Andrew, Georgia ;

Mukherjee, Devdeep ;

Wong, Zoe ;

Auletta, Jeffery J. ;

El Chaer, Firas ;

Chen, Evan C. ;

Chen, Yi-Bin ;

Corner, Adam ;

Devine, Steven M. ;

Iyer, Sunil G. ;

Jimenez, Antonio Martin Jimenez ;

De Lima, Marcos J. G. ;

Litzow, Mark R. ;

Kebriaei, Partow ;

Saber, Wael ;

Spellman, Stephen R. ;

Zeger, Scott L. ;

Page, Kristin M. ;

Dillon, Laura W. ;

Hourigan, Christopher S. .

BONE MARROW TRANSPLANTATION, 2025, 60 (02) :144-153

[10] Therapy for isocitrate dehydrogenase 2 (IDH2)R172-mutant acute myeloid leukaemia [J].

Linch, David C. ;

Hills, Robert K. ;

Burnett, Alan K. ;

Russell, Nigel ;

Gale, Rosemary E. .

BRITISH JOURNAL OF HAEMATOLOGY, 2022, 196 (06) :1348-1352

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