A Prospective Controlled Study on the Longitudinal Effects of Rehabilitation in Older Women with Primary Sarcopenia

被引:0
作者
Vladutu, Bianca Maria [1 ]
Matei, Daniela [2 ]
Amzolini, Anca Maria [3 ]
Kamal, Constantin [4 ]
Traistaru, Magdalena Rodica [2 ]
机构
[1] Univ Med & Pharm Craiova, Doctoral Sch, Craiova 200349, Romania
[2] Univ Med & Pharm Craiova, Dept Med Rehabil, Craiova 200349, Romania
[3] Univ Med & Pharm Craiova, Dept Med Semiol, Craiova 200349, Romania
[4] Univ Med & Pharm Craiova, Dept Family Med, Craiova 200349, Romania
来源
LIFE-BASEL | 2025年 / 15卷 / 04期
关键词
sarcopenia; physical performance; health-related quality of life; personalized rehabilitation; older adults; SarQoL; SPPB; QUESTIONNAIRE; DEFINITION; MORTALITY; DIAGNOSIS; CONSENSUS; MOBILITY; UPDATE; MASS;
D O I
10.3390/life15040609
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Sarcopenia, defined as a progressive loss of skeletal muscle mass, strength, and function, is a leading contributor to disability, dependence, and reduced quality of life (HRQoL) in older adults. This study aimed to evaluate the impact of a personalized six-month rehabilitation program, centered on tailored kinetic therapy, on physical performance and HRQoL in older women with primary sarcopenia. Methods: This prospective controlled study included 80 women aged >= 65 years, allocated into a Study Group (SG, n = 40), who followed a supervised personalized kinetic program, and a control group (CG, n = 40), who received general advice regarding physical activity and nutrition. Physical performance was measured using the short physical performance battery (SPPB), while HRQoL was assessed with the disease-specific SarQoL questionnaire. Evaluations were conducted at baseline and after six months. Results: At baseline, both groups had comparable scores (SPPB: SG = 5.75 +/- 0.86 vs. CG = 5.8 +/- 0.88, p = 0.798; SarQoL: SG = 54.42 +/- 8.76 vs. CG = 55.59 +/- 4.61, p = 0.457). After six months, the SG showed significant improvements (SPPB = 8.05 +/- 0.90, p < 0.001; SarQoL = 62.55 +/- 7.00, p < 0.001). Significant gains were observed in domains related to physical and mental health, locomotion, functionality, and leisure activities (p < 0.05). In contrast, the CG showed only minor, non-significant changes (SPPB = 6.17 +/- 0.78; SarQoL = 56.51 +/- 5.51). Conclusions: A structured, personalized kinetic program significantly improves physical performance and HRQoL in older women with primary sarcopenia. These results support the need for individualized, supervised rehabilitation programs in optimizing functional recovery and enhancing patient-centered outcomes in sarcopenia management.
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页数:25
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