Age-Related Long-Term Longitudinal Changes in Left Ventricular Mechanical Function in Breast Cancer Patients Undergoing Anthracycline and Trastuzumab Treatment

被引：0

作者：

Akbalaeva, Begimai ^{[1
]}

Singh, Priti ^{[2
]}

Khan, Salman ^{[3
,4
]}

机构：

[1] Osh State Univ, Int Med Fac, Dept Clin Disciplines 1, Osh, Kyrgyzstan

[2] Amer Univ, Sch Med Aruba, Dept Premed Sci & Nutr, Biochem & Mol Sci, Oranjestad, Aruba

[3] Amer Univ, Sch Med Aruba, Dept Pathol Proc & Therapeut, Oranjestad, Aruba

[4] Osh State Univ, Int Med Fac, Osh, Kyrgyzstan

来源：

CLINICAL CASE REPORTS | 2025年 / 13卷 / 04期

关键词：

anthracycline; breast cancer; cardiotoxicity; chemotherapy; speckle-tracking echocardiography; trastuzumab; CARDIOTOXICITY; STRAIN;

D O I：

10.1002/ccr3.70451

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Age significantly influences the severity of chemotherapy-induced cardiotoxicity (cardiotoxicity) in HER2-positive breast cancer patients. Comprehensive cardiac monitoring before, during, and after anthracycline and trastuzumab regimens is essential. Tailored assessments can help identify vulnerable patients, optimize treatment, and mitigate risks of heart complications while maintaining therapy efficacy.

引用

页数：6

共 16 条

[1]

Abe O, 2005, LANCET, V366, P2087, DOI 10.1016/s0140-6736(05)66544-0

[2] Effect of screening and adjuvant therapy on mortality from breast cancer [J].

Berry, DA ;

Cronin, KA ;

Plevritis, SK ;

Fryback, DG ;

Clarke, L ;

Zelen, M ;

Mandelblatt, JS ;

Yakovlev, AY ;

Habbema, JDF ;

Feuer, EJ .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (17) :1784-1792

[3] Two-dimensional speckle tracking echocardiography predicts early subclinical cardiotoxicity associated with anthracycline-trastuzumab chemotherapy in patients with breast cancer [J].

Calle, Maria C. Arciniegas ;

Sandhu, Nicole P. ;

Xia, Hongmei ;

Cha, Stephen S. ;

Pellikka, Patricia A. ;

Ye, Zi ;

Herrmann, Joerg ;

Villarraga, Hector R. .

BMC CANCER, 2018, 18

[4]

European Society of Cardiology, 2024, Clinical Practice Guidelines

[5] Left Ventricular Global Longitudinal Strain in HER-2+Breast Cancer Patients Treated with Anthracyclines and Trastuzumab Who Develop Cardiotoxicity Is Associated with Subsequent Recovery of Left Ventricular Ejection Fraction [J].

Fei, Hong-wen ;

Ali, Mohammed T. ;

Tan, Timothy C. ;

Cheng, Kai-Hung ;

Salama, Laura ;

Hua, Lanqi ;

Zeng, Xin ;

Halpern, Elkan F. ;

Taghian, Alphonse ;

MacDonald, Shannon M. ;

Scherrer-Crosbie, Marielle .

ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 2016, 33 (04) :519-526

[6] Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012 [J].

Ferlay, Jacques ;

Soerjomataram, Isabelle ;

Dikshit, Rajesh ;

Eser, Sultan ;

Mathers, Colin ;

Rebelo, Marise ;

Parkin, Donald Maxwell ;

Forman, David ;

Bray, Freddie .

INTERNATIONAL JOURNAL OF CANCER, 2015, 136 (05) :E359-E386

[7] Echocardiographic Assessment of Left Ventricular Function in Three Oncologic Therapeutic Modalities in Women with Breast Cancer: The ONCO-ECHO Multicenter Study [J].

Gasior, Tomasz ;

Zaborska, Beata ;

Stachowiak, Pawel ;

Sikora-Frac, Malgorzata ;

Mizia-Stec, Katarzyna ;

Kasprzak, Jaroslaw ;

Bodys, Artur ;

Bijoch, Julia ;

Szmagala, Adrianna ;

Kosior, Dariusz A. ;

Plonska-Gosciniak, Edyta .

JOURNAL OF CLINICAL MEDICINE, 2024, 13 (09)

[8] Obesity As a Risk Factor for Anthracyclines and Trastuzumab Cardiotoxicity in Breast Cancer: A Systematic Review and Meta-Analysis [J].

Guenancia, Charles ;

Lefebvre, Annick ;

Cardinale, Daniela ;

Yu, Anthony F. ;

Ladoire, Sylvain ;

Ghiringhelli, Francois ;

Zeller, Marianne ;

Rochette, Luc ;

Cottin, Yves ;

Vergely, Catherine .

JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (26) :3157-+

[9]

Hadzibeganovic Amina, 2023, Acta Med Acad, V52, P225, DOI 10.5644/ama2006-124.417

[10] Early Detection and Prediction of Cardiotoxicity in Chemotherapy-Treated Patients [J].

Sawaya, Heloisa ;

Sebag, Igal A. ;

Plana, Juan Carlos ;

Januzzi, James L. ;

Ky, Bonnie ;

Cohen, Victor ;

Gosavi, Sucheta ;

Carver, Joseph R. ;

Wiegers, Susan E. ;

Martin, Randolph P. ;

Picard, Michael H. ;

Gerszten, Robert E. ;

Halpern, Elkan F. ;

Passeri, Jonathan ;

Kuter, Irene ;

Scherrer-Crosbie, Marielle .

AMERICAN JOURNAL OF CARDIOLOGY, 2011, 107 (09) :1375-1380

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