Visible light-induced perfluoroalkylation reaction of indoles in the presence of Na2-eosin Y

被引：0

作者：

He, Xiang-Wu ^{[1
,2
]}

Du, Chen ^{[3
,4
]}

Liu, Zhen-Jiang ^{[1
]}

Jiang, Min ^{[2
]}

Liu, Jin-Tao ^{[2
]}

机构：

[1] Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China

[2] Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Fluorine & Nitrogen Chem & Adv Mat, 345 Lingling Rd, Shanghai 200032, Peoples R China

[3] Shanghai Normal Univ, Educ Minist, Key Lab Resource Chem, Shanghai 200234, Peoples R China

[4] Shanghai Normal Univ, Shanghai Key Lab Rare Earth Funct Mat, Shanghai 200234, Peoples R China

来源：

TETRAHEDRON LETTERS | 2025年 / 162卷

基金：

中国国家自然科学基金;

关键词：

Visible light; Perfluoroalkylation; Indole; Na2-eosin Y; SYNTHETIC APPLICATIONS; PHOTOREDOX CATALYSIS; ORGANIC-DYES; TRIFLUOROMETHYLATION; CYCLIZATION; THIOETHERS; FLUORINE; ETHERS;

D O I：

10.1016/j.tetlet.2025.155571

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Visible light-induced perfluoroalkylation reaction of 3-substituted indoles using Na2-Eosin Y as photoredox catalysis was achieved under mild conditions to give a series of C2-perfluoroalkylated indoles in moderate to good yields. Under similar conditions, both C3 and C4 perfluoroalkylation reactions of 2-substituted indoles occurred to produce two regioisomers. The reaction of unsubstituted indole gave the C2 and C3 perfluoroalkylation products. A possible pathway was proposed based on the experimental results.

引用

页数：4

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