Neurogenic Bladder in Children with Myelomeningocele

被引:0
作者
Sic, Aleksandar [1 ]
Stojanovic, Borko [1 ,2 ]
Dordevic, Miroslav [1 ,2 ,3 ]
机构
[1] Univ Belgrade, Fac Med, Belgrade 11000, Serbia
[2] Univ Childrens Hosp, Dept Urol, Belgrade 11000, Serbia
[3] Icahn Sch Med Mt Sinai, Dept Urol, New York, NY 10029 USA
关键词
myelomeningocele; neurogenic bladder; urodynamics; CIC; CLEAN INTERMITTENT CATHETERIZATION; PRIMARY VESICOURETERAL REFLUX; URINARY-TRACT-INFECTION; AUGMENTATION CYSTOPLASTY; SPINA-BIFIDA; MANAGEMENT; CARE; NEUROMODULATION; EPIDEMIOLOGY; DYSFUNCTION;
D O I
10.3390/diseases13040117
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Myelomeningocele (MMC), a severe congenital anomaly resulting from neural tube closure defects, poses significant urological challenges necessitating specialized care. This review explores the intricate landscape of MMC within urological practice, advocating for a multidisciplinary approach to optimize patient outcomes. By surveying diverse treatment modalities, this review aims to offer insights into enhancing urological management strategies for MMC and guiding future research directions. At the heart of the conversation lies the pathophysiology of neurogenic bladder dysfunction in children with MMC, with a particular focus on the complexities of diagnosis and the various paradigms guiding urological management. Common complications such as recurrent urinary tract infections are examined alongside non-surgical interventions like intermittent catheterization (CIC) and pharmacotherapy, notably oxybutynin. Additionally, surgical options including botulinum toxin injection and reconstructive procedures are explored to enhance urological outcomes for affected children. By unpacking the complexities of neurogenic bladder dysfunction in MMC, this review emphasizes the imperative of a collaborative, multidisciplinary approach in urological care, ultimately aiming to enhance patient well-being and functional outcomes.
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页数:15
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