Influenza vaccine effectiveness among primary and secondary school students in Shenzhen during the 2023/24 influenza season

被引：0

作者：

Jiang, Yawen ^{[1
]}

Sun, Jiatong ^{[1
]}

Huang, Fang ^{[2
]}

Xie, Xu ^{[2
]}

Wang, Xin ^{[2
]}

Wu, Xiaoliang ^{[2
]}

Jiang, Min ^{[2
]}

Sun, Ying ^{[2
]}

Liu, Hui ^{[2
]}

Gu, Huiqiao ^{[1
]}

Lu, Quan ^{[3
]}

Chen, Xiaozhen ^{[4
]}

Feng, Tiejian ^{[2
]}

Fang, Shisong ^{[2
]}

Lu, Jianhua ^{[2
]}

Shu, Yuelong ^{[1
,5
]}

机构：

[1] Sun Yat sen Univ, Sch Publ Hlth Shenzhen, Shenzhen, Peoples R China

[2] Shenzhen Ctr Dis Control & Prevent, Shenzhen 518055, Peoples R China

[3] Peoples Hosp Baoan Dist, Dept Prevent Hlth Care, Shenzhen, Peoples R China

[4] Shenzhen Childrens Hosp, Dept Prevent Hlth Care, Shenzhen, Peoples R China

[5] Chinese Acad Med Sci & Peking Union Med Coll, Natl Inst Pathogen Biol, State Key Lab Resp Hlth & Multimorbid, Key Lab Pathogen Infect Prevent & Control MOE, Beijing 102629, Peoples R China

来源：

EMERGING MICROBES & INFECTIONS | 2025年 / 14卷 / 01期

关键词：

Seasonal influenza; vaccine effectiveness; primary and secondary school students; public health; test-negative case-control study; HOSPITALIZATION; PROTECTION; CHILDREN; CHINA;

D O I：

10.1080/22221751.2025.2490531

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During the winter influenza peaks, a total of 2689 ILI patients were collected from the two hospitals, with 58.61% of the participants vaccinated. Of the ILI patients, 761 (28.3%) were laboratory-confirmed influenza infection, with 76.7% being A(H3N2) and 22.8% B/Victoria. After adjusting for covariates, the adjusted VE (aVE) was 57.06% (95% CI, 48.59-64.13%). In the subtype/lineage and age subgroup analysis, influenza VE against B/Victoria was higher than A(H3N2), and decreased with age. More, influenza VE (aVE = 19.63% [95% CI, -29.13-49.98%]) against all subtypes/lineages were not statistically significant for the spring-summer peak. Overall, influenza vaccines provided significant protection against influenza-associated outpatient visits among students in Shenzhen during 2023/24 winter influenza season. The findings underscore the importance of maintaining high vaccination coverage.

引用

页数：11

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