Exploring Paediatric Jaw Osteosarcoma: A Detailed Case Report of a 12-Year-Old Girl and Review of the Literature

被引:1
作者
Simpson, Jessica [1 ]
Sallies, Moegamat [2 ]
Afrogheh, Amir H. [3 ,4 ,5 ]
机构
[1] Univ Western Cape, Fac Dent, Dept Craniofacial Biol Pathol & Radiol, Cape Town, South Africa
[2] Univ Western Cape, Fac Dent, Dept Oral & Maxillofacial Surg, Cape Town, South Africa
[3] Stellenbosch Univ, Div Anat Pathol, Cape Town, South Africa
[4] Univ Western Cape, Dept Oral & Maxillofacial Pathol, Natl Hlth Lab Serv, Cape Town, South Africa
[5] Tygerberg Hosp, Natl Hlth Lab Serv, Cape Town, South Africa
关键词
case report; malignancy; oral pathology; osteosarcoma; paediatric dentistry; EPITHELIOID OSTEOSARCOMA;
D O I
10.1155/crid/7428891
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Osteosarcoma, the most common primary bone malignancy, rarely affects the jaw, representing only 6%-10% of cases. Jaw osteosarcoma typically occurs in individuals between the ages of 30 and 50 years and is uncommon in children. It often involves the mandible, especially in males, presenting with swelling, tooth mobility, and paraesthesia rather than pain. We present a rare case of jaw osteosarcoma in a 12-year-old girl who exhibited paraesthesia and a significant mandibular mass. Imaging demonstrated extensive mandibular involvement with Codman's triangle formation, and a biopsy confirmed the diagnosis of conventional osteosarcoma. The treatment approach included a hemimandibulectomy, followed by temporary reconstruction using a titanium plate and silastic spacer. This case underscores the importance of comprehensive evaluation and multidisciplinary management in diagnosing and treating osteosarcoma of the jaws in children. A review of 12 similar cases highlights the variability in presentation and treatment outcomes, emphasizing the need for individualized treatment plans to optimize patient prognosis.
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页数:9
相关论文
共 30 条
[1]   Osteosarcoma of mandible: Detailed radiographic assessment of a case [J].
Arora, Piyush ;
Rehman, Farzan ;
Girish, K. L. ;
Kalra, Manpreet .
CONTEMPORARY CLINICAL DENTISTRY, 2013, 4 (03) :382-385
[2]   Osteosarcoma of the jaws: An overview of the pathophysiological mechanisms [J].
Bertin, Helios ;
Gomez-Brouchet, A. ;
Redini, F. .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2020, 156
[3]  
BERTONI F, 1991, CANCER-AM CANCER SOC, V68, P1555, DOI 10.1002/1097-0142(19911001)68:7<1555::AID-CNCR2820680717>3.0.CO
[4]  
2-0
[5]   Case Report: A Pediatric Case of Cementoblastoma with Histologic and Radiographic Features of an Osteoblastoma and Osteosarcoma [J].
Bilodeau E. ;
Collins B. ;
Costello B. ;
Potluri A. .
Head and Neck Pathology, 2010, 4 (4) :324-328
[6]   Osteosarcoma of the Taws: Report of 3 cases with emphasis on we early emphasis on we early clinical and radiographic signs [J].
Charmelo-Silva, Scarlet ;
Buchanan, Allison ;
Kalathingal, Sajitha ;
Abdelsayed, Rafik .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 2022, 133 (02) :E57-E62
[7]  
Chaudhary Mayur, 2012, J Oral Maxillofac Pathol, V16, P233, DOI 10.4103/0973-029X.99075
[8]   Osteosarcoma (osteogenic sarcoma) of the jaws presenting in general dental practice - a series of four cases [J].
Costello, Liam ;
Toner, Mary ;
Pierse, Dermot ;
Stassen, Leo F. A. .
BRITISH DENTAL JOURNAL, 2021, 230 (09) :583-586
[9]   Epithelioid Osteosarcoma of the Jaw [J].
Cozza, Raffaele ;
Devito, Rita ;
De Loris, Maria Antonietta ;
Zama, Mario ;
Boldrini, Renata ;
Fidani, Paola ;
Donfrancesco, Alberto .
PEDIATRIC BLOOD & CANCER, 2009, 52 (07) :877-879
[10]  
Donaldson M E, 2004, Int J Paediatr Dent, V14, P54, DOI 10.1111/j.1365-263X.2004.00519.x