Discrete-time competing-risks regression with or without penalization

被引:0
|
作者
Meir, Tomer [1 ]
Gorfine, Malka [2 ]
机构
[1] Technion Israel Inst Technol, Dept Data & Decis Sci, IL-3200003 Haifa, Israel
[2] Tel Aviv Univ, Dept Stat & Operat Res, IL-6997801 Tel Aviv, Israel
关键词
competing events; penalized regression; regularized regression; sure independent screening; survival analysis; LENGTH-OF-STAY; MODELS; PREDICTION;
D O I
10.1093/biomtc/ujaf040
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Many studies employ the analysis of time-to-event data that incorporates competing risks and right censoring. Most methods and software packages are geared towards analyzing data that comes from a continuous failure time distribution. However, failure-time data may sometimes be discrete either because time is inherently discrete or due to imprecise measurement. This paper introduces a new estimation procedure for discrete-time survival analysis with competing events. The proposed approach offers a major key advantage over existing procedures and allows for straightforward integration and application of widely used regularized regression and screening-features methods. We illustrate the benefits of our proposed approach by a comprehensive simulation study. Additionally, we showcase the utility of the proposed procedure by estimating a survival model for the length of stay of patients hospitalized in the intensive care unit, considering 3 competing events: discharge to home, transfer to another medical facility, and in-hospital death. A Python package, PyDTS, is available for applying the proposed method with additional features.
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页数:12
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