AP5Z1 affects hepatocellular carcinoma growth and autophagy by regulating PTEN ubiquitination and modulating the PI3K/Akt/mTOR pathway

被引：0

作者：

Zhipeng Quan ^{[1
]}

Bo Peng ^{[2
]}

Kai Hu ^{[3
]}

Lixing Liang ^{[1
]}

Mingjiang Liu ^{[2
]}

Lijuan Liao ^{[3
]}

Shilian Chen ^{[3
]}

Jing Qin ^{[4
]}

Songqing He ^{[3
]}

Zeyuan Li ^{[4
]}

机构：

[1] The First Affiliated Hospital of Guangxi Medical University,Division of Hepatobiliary Surgery

[2] Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor (Guangxi Medical University,Department of Radiation Oncology

[3] Ministry of Education,undefined

[4] Guangxi Key Laboratory of Immunology and Metabolism for Liver Diseases,undefined

[5] The First Affiliated Hospital of Guangxi Medical University,undefined

来源：

关键词：

Hepatocellular carcinoma; PTEN; TRIM21; Autophagy; Apoptosis; PI3K/Akt/mTOR signalling pathway; Ubiquitination;

D O I：

10.1186/s12967-025-06537-9

中图分类号：

学科分类号：

摘要：

引用