Correlation between dyslipidaemia and gastric cancer: pathogenesis to prevention and treatment strategies

被引：0

作者：

Tao Wu ^{[1
]}

Lingna Zhang ^{[2
]}

Jiao Tian ^{[1
]}

Yuyuan Lu ^{[1
]}

Yan Yang ^{[1
]}

Xin Yang ^{[4
]}

Penghui Jin ^{[3
]}

Yuanhui Gu ^{[3
]}

Xiaoke Wang ^{[2
]}

Lin Yi ^{[2
]}

机构：

[1] Gansu University of Chinese Medicine,School of Traditional Chinese and Western Medicine

[2] Gansu Provincial Hospital,Department of General Surgery

[3] Gansu University of Chinese Medicine,First School of Clinical Medicine

[4] Gansu Provincial Hospital,Pharmacy Department

来源：

Lipids in Health and Disease | / 24卷 / 1期

关键词：

Dyslipidaemia; Gastric cancer; Apolipoproteins; Atherosclerosis; Statins;

D O I：

10.1186/s12944-025-02625-3

中图分类号：

学科分类号：

摘要：

As the sixth most common cancer in the world, the development of gastric cancer (GC) is influenced by many factors. Recent studies have revealed a strong association between dyslipidaemia and GC. In this paper, the relationships between dyslipidaemia and GC are discussed in depth. We review the development of GC through the mechanisms of the inflammatory response, signalling pathways, and apolipoprotein function, and the intersecting targets of atherosclerosis and GC are explored. The synergistic effects of Helicobacter pylori infection and dyslipidaemia on the development of GC are also analysed, and the potential value of statins in the prevention and treatment of GC is discussed. In this review, we systematically investigated the relationship between dyslipidaemia and GC to provide new ideas for GC prevention and treatment.

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