Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study

被引：0

作者：

Setiati, Siti ^{[1
]}

Harimurti, Kuntjoro ^{[1
]}

Fitriana, Ika ^{[1
]}

Dwimartutie, Noto ^{[1
]}

Istanti, Rahmi ^{[1
]}

Azwar, Muhammad Khifzhon ^{[1
]}

Aryana, I. Gusti Putu Suka ^{[2
]}

Sunarti, Sri ^{[3
]}

Sudarso, Agus ^{[4
]}

Ariestine, Dina Aprillia ^{[5
]}

Dwipa, Lazuardhi ^{[6
]}

Widajanti, Novira ^{[7
]}

Riviati, Nur ^{[8
]}

Mulyana, Roza ^{[9
]}

Rensa, Rensa ^{[10
]}

Mupangati, Yudo Murti ^{[11
]}

Budiningsih, Fatichati ^{[12
]}

Sari, Nina Kemala ^{[1
]}

机构：

[1] Univ Indonesia, Cipto Mangunkusumo Hosp, Dept Internal Med, Div Geriatr Med,Fac Med, Jakarta, Indonesia

[2] Univ Udayana, Fac Med, Dept Internal Med, Denpasar, Indonesia

[3] Univ Brawijaya, Fac Med, Dept Internal Med, Malang, Indonesia

[4] Univ Hasanuddin, Fac Med, Dept Internal Med, Makassar, Indonesia

[5] Univ Sumatera Utara, Fac Med, Dept Internal Med, Medan, Indonesia

[6] Univ Padjadjaran, Fac Med, Dept Internal Med, Bandung, Indonesia

[7] Univ Airlangga, Fac Med, Dept Internal Med, Surabaya, Indonesia

[8] Univ Sriwijaya, Fac Med, Dept Internal Med, Palembang, Indonesia

[9] Univ Andalas, Fac Med, Dept Internal Med, Padang, Indonesia

[10] Atma Jaya Catholic Univ Indonesia, Sch Med & Hlth Sci, North Jakarta, Indonesia

[11] Univ Diponegoro, Fac Med, Dept Internal Med, Semarang, Indonesia

[12] Univ Sebelas Maret, Fac Med, Dept Internal Med, Surakarta, Indonesia

来源：

ANNALS OF GERIATRIC MEDICINE AND RESEARCH | 2025年 / 29卷 / 01期

关键词：

Cognitive dysfunction; Frailty; Indonesia; Malnutrition; Sarcopenia; Stroke; ASIAN WORKING GROUP; ALZHEIMERS-DISEASE; NUTRITIONAL-STATUS; INFLAMMATION; OUTCOMES;

D O I：

10.4235/agmr.24.0144

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Background: The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients. Methods: We collected data from community-dwelling outpatients aged >= 60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively. Results: The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48-20.61), cognitive impairment (OR=3.70, 95% CI 1.21-11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38-39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status. Conclusion: Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary.

引用

页码：91 / 101

页数：11

共 50 条

[1]

Almirall Jose, 2013, J Comorb, V3, P4

[2] Chronic low-grade inflammation and age-related sarcopenia [J].