Recent progress of carbon-based quantum dots and nanotubes for cancer targeting and drug delivery applications

被引:0
作者
Mondal, Sudipta [1 ,2 ]
Das, Subhadeep [3 ,4 ]
Sharma, Binayok [5 ]
Nayak, Rajashree [6 ]
Rahman, Md Zillur [7 ]
机构
[1] Purdue Univ, Sch Mat Engn, W Lafayette, IN 47907 USA
[2] Bangladesh Univ Engn & Technol, Dept Mat & Met Engn, Dhaka 1000, Bangladesh
[3] Purdue Univ, Dept Biochem, BCHM A343,175 S Univ St, W Lafayette, IN 47907 USA
[4] Purdue Univ, Inst Canc Res, Hansen Life Sci Res Bldg,Room 141,201 S Univ St, W Lafayette, IN 47907 USA
[5] Purdue Univ, Dept Anim Sci, W Lafayette, IN 47907 USA
[6] Indian Inst Sci Educ & Res, Pune 411008, India
[7] Ahsanullah Univ Sci & Technol, Dept Mech Engn, Dhaka 1208, Bangladesh
关键词
Carbon dot; Carbon nanotube; Nano materials; Cancer; Drug delivery; DOXORUBICIN-TRANSFERRIN CONJUGATE; ANTICANCER DRUG; GENE DELIVERY; RELEASE; GEMCITABINE; PACLITAXEL; SYSTEM; CELLS; DNA; NANOPARTICLES;
D O I
10.1016/j.jddst.2025.106896
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Cancer remains a major global health challenge, driving extensive research into developing advanced nano systems for precise and effective drug delivery. Carbon-based nanomaterials, particularly carbon nanotubes and quantum dots, have gained prominence due to their exceptional structural and physicochemical properties. These nanomaterials offer significant advantages, including high drug-loading capacity, enhanced biocompatibility, and reduced immunogenicity, making them highly promising candidates for cancer therapy. This review provides a detailed examination of the synthesis and functionalization of carbon nanostructures, highlighting recent advancements in their use for cancer drug delivery. Also, it analyzes their potential to improve therapeutic outcomes through targeted delivery mechanisms while addressing the challenges associated with their clinical translation. Furthermore, the review explores the prospects, challenges, and future directions of carbon nanotubes and quantum dots, focusing on their integration into clinical applications for cancer treatment.
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页数:16
相关论文
共 155 条
[91]   Folate-Conjugated PEG on Single Walled Carbon Nanotubes for Targeting Delivery of Doxorubicin to Cancer Cells [J].
Niu, Lvye ;
Meng, Lingjie ;
Lu, Qinghua .
MACROMOLECULAR BIOSCIENCE, 2013, 13 (06) :735-744
[92]   Recent advances in carbon quantum dots for gene delivery: A comprehensive review [J].
Othman, Hazha Omar ;
Anwer, Esra Tariq ;
Ali, Diyar Salahuddin ;
Hassan, Rebwar Omar ;
Mahmood, Elnaz Ehsan ;
Ahmed, Rayan Abubakir ;
Muhammad, Rozhan Fathulla ;
Smaoui, Slim .
JOURNAL OF CELLULAR PHYSIOLOGY, 2024, 239 (11)
[93]  
Oyshi M.T., 2024, Emerging Sustainable Nanomaterials for Biomedical Applications, P41
[94]   Cancer Targeting and Drug Delivery Using Carbon-Based Quantum Dots and Nanotubes [J].
Pardo, Joel ;
Peng, Zhili ;
Leblanc, Roger M. .
MOLECULES, 2018, 23 (02)
[95]   Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay [J].
Parker, N ;
Turk, MJ ;
Westrick, E ;
Lewis, JD ;
Low, PS ;
Leamon, CP .
ANALYTICAL BIOCHEMISTRY, 2005, 338 (02) :284-293
[96]   Green Synthesis of Value-Added Fluorescent Carbon Dots from Sugarcane Bagasse and Their Antioxidant, Reducing and Catalytic Activities [J].
Parveen, Shehla ;
Bukhari, Naeema ;
Ramzan, Noreen ;
Musaddiq, Sara ;
Mubarak, Shamroza ;
Kalsoom, Ambreen ;
Qureshi, Waseem Akhtar .
SUGAR TECH, 2024, 26 (01) :33-44
[97]   Carbon dots: promising biomaterials for bone-specific imaging and drug delivery [J].
Peng, Zhili ;
Miyanji, Esmail H. ;
Zhou, Yiqun ;
Pardo, Joel ;
Hettiarachchi, Sajini D. ;
Li, Shanghao ;
Blackwelder, Patricia L. ;
Skromne, Isaac ;
Leblanc, Roger M. .
NANOSCALE, 2017, 9 (44) :17533-17543
[98]   Degradation or excretion of quantum dots in mouse embryonic stem cells [J].
Pi, Qing Meng ;
Zhang, Wen Jie ;
Zhou, Guang Dong ;
Liu, Wei ;
Cao, Yilin .
BMC BIOTECHNOLOGY, 2010, 10
[99]   Novel carbon quantum dots incorporated polyacrylic acid/polyethylene glycol pH-sensitive nanoplatform for drug delivery [J].
Pourmadadi, Mehrab ;
Tajiki, Alireza ;
Abdouss, Majid ;
Mohammadi, Alireza Beig ;
Kharaba, Zelal ;
Rahdar, Abbas ;
Diez-Pascual, Ana M. .
INORGANIC CHEMISTRY COMMUNICATIONS, 2024, 159
[100]   Chiral nanomaterial-based approaches for diagnosis and treatment of protein-aggregated neurodiseases: current status and future opportunities [J].
Pranav ;
Bajpai, Abhishek ;
Dwivedi, Prabhat K. ;
Sivakumar, Sri .
JOURNAL OF MATERIALS CHEMISTRY B, 2024, 12 (08) :1991-2005