Advances in endovascular thrombectomy for the treatment of acute ischemic stroke

被引：0

作者：

Lauer, David ^{[1
,2
,3
]}

Sulzenko, Jakub ^{[2
,4
]}

Malikova, Hana ^{[1
,2
]}

Stetkarova, Ivana ^{[2
,3
]}

Widimsky, Petr ^{[2
,4
]}

机构：

[1] Charles Univ Prague, Fac Med 3, Dept Radiol & Nucl Med, Ruska 87, Prague 10, Czech Republic

[2] Univ Hosp Kralovske Vinohrady, Ruska 87, Prague 10, Czech Republic

[3] Charles Univ Prague, Fac Med 3, Dept Neurol, Prague, Czech Republic

[4] Charles Univ Prague, Fac Med 3, Dept Cardiol, Prague, Czech Republic

来源：

EXPERT REVIEW OF NEUROTHERAPEUTICS | 2025年 / 25卷 / 06期

关键词：

ASPECTS; acute ischemic stroke; endovascular thrombectomy; expanded therapeutic window; large infarction; large vessel occlusion; posterior circulation stroke; thrombectomy techniques; STENT-RETRIEVER THROMBECTOMY; LARGE VESSEL OCCLUSION; TREATMENT POSITION PAPER; BALLOON GUIDE CATHETER; MECHANICAL THROMBECTOMY; INTRAVENOUS THROMBOLYSIS; CLINICAL-OUTCOMES; MEDICAL THERAPY; OPEN-LABEL; TRIAL;

D O I：

10.1080/14737175.2025.2490538

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

IntroductionAcute ischemic stroke (AIS) is the second leading cause of death and one of the leading causes of long-term disability globally. Endovascular thrombectomy (EVT) has revolutionized treatment for large vessel occlusion (LVO), providing 20% increase in post-stroke functional independence compared to intravenous thrombolysis (IVT) alone. Despite its proven efficacy, EVT is underutilized. While it is suitable for at least 15-20% of AIS patients, its mean adoption ranges from less than 1% to 7% in different areas.Areas coveredThis review highlights key findings from pivotal randomized controlled trials and real-world data, focusing on patient selection criteria, advancements in thrombectomy devices, and procedural innovations. A comprehensive literature search was performed using PubMed, Scopus, EMBASE and the Cochrane Library for relevant randomized controlled trials and observational studies.Expert opinionDisparity in access to EVT requires strategic investments in healthcare systems and international multidisciplinary collaboration. Enhancing geographic coverage with thrombectomy-capable centers and optimizing prehospital triage systems are essential. Bridging the gap between treatment capability and real-world implementation is critical to improving global AIS outcomes.

引用

页码：675 / 687

页数：13

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