Simultaneous Occurrence of Hyponatremia and Hypokalemia in a Patient with Herpes Zoster: A Case Report with a Review of the Literature

被引：0

作者：

Yamagata, Satoshi ^{[1
,2
]}

Kageyama, Kazunori ^{[1
,3
]}

Yanagimachi, Miyuki ^{[1
]}

Murakami, Hiroshi ^{[1
]}

Daimon, Makoto ^{[1
]}

机构：

[1] Hirosaki Univ, Grad Sch Med, Dept Endocrinol & Metab, Hirosaki, Japan

[2] Columbia Univ, Inst Human Nutr, Irving Med Ctr, New York, NY 10032 USA

[3] Tohoku Med & Pharmaceut Univ, Div Nephrol & Endocrinol, Sendai, Japan

来源：

INTERNAL MEDICINE | 2025年 / 64卷 / 02期

关键词：

VZV; SIAD; hyponatremia; hypokalemia; stress; cortisol; CORTICOTROPIN-RELEASING-FACTOR; CLINICAL-PRACTICE GUIDELINE; POSTHERPETIC NEURALGIA; OPHTHALMICUS; DIAGNOSIS; PAIN;

D O I：

10.2169/internalmedicine.3795-24

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We herein report a patient with herpes zoster (HZ), severe hyponatremia, and hypokalemia. Syndrome of inappropriate antidiuresis (SIAD) leads to euvolemic hyponatremia and hypoosmotic plasma due to inadequate diuresis. Hyponatremia in the current patient was caused by SIAD and associated with HZ of the trigeminal facial nerve (V1). The patient also had hypokalemia, with excessive urinary potassium excretion and elevated cortisol levels. Hypokalemia is caused by hypercortisolemia, which is stimulated by HZ pain. Adequate treatment for HZ and comprehensive pain control play pivotal roles in improving SIAD, cortisol hypersecretion, and the subsequent electrolyte abnormalities.

引用

页码：261 / 266

页数：6

共 32 条

[1]

Alper BS, 2000, J FAM PRACTICE, V49, P255

[2] Diagnostic accuracy of the different hormonal tests used for the diagnosis of autonomous cortisol secretion [J].

Araujo-Castro, Marta ;

Cano, Ana Garcia ;

Jimenez Mendiguchia, Lucia ;

Escobar-Morreale, Hector F. ;

Valderrabano, Pablo .

SCIENTIFIC REPORTS, 2021, 11 (01)

[3] Upregulation of the hypothalamo-neurohypophysial system and activation of vasopressin neurones attenuates hyperalgesia in a neuropathic pain model rat [J].

Baba, Kazuhiko ;

Kawasaki, Makoto ;

Nishimura, Haruki ;

Suzuki, Hitoshi ;

Matsuura, Takanori ;

Ikeda, Naofumi ;

Fujitani, Teruaki ;

Yamanaka, Yoshiaki ;

Tsukamoto, Manabu ;

Ohnishi, Hideo ;

Yoshimura, Mitsuhiro ;

Maruyama, Takashi ;

Sanada, Kenya ;

Sonoda, Satomi ;

Nishimura, Kazuaki ;

Tanaka, Kentaro ;

Onaka, Tatsushi ;

Ueta, Yoichi ;

Sakai, Akinori .

SCIENTIFIC REPORTS, 2022, 12 (01)

[4]

Bassi V, 2017, OXF MED CASE REP, P223, DOI 10.1093/omcr/omx065

[5] Is the syndrome of inappropriate secretion of antidiuretic hormone responsible for hyponatremia in a patient with herpes varicella zoster virus? [J].

Calenda, E ;

Muraine, M ;

Dessole, E .

SOUTHERN MEDICAL JOURNAL, 1996, 89 (12) :1224-1224

[6] 11β-HYDROXYSTEROID DEHYDROGENASES: INTRACELLULAR GATE-KEEPERS OF TISSUE GLUCOCORTICOID ACTION [J].

Chapman, Karen ;

Holmes, Megan ;

Seckl, Jonathan .

PHYSIOLOGICAL REVIEWS, 2013, 93 (03) :1139-1206

[7] Severe hyponatraemia in medical in-patients: aetiology, assessment and outcome [J].

Clayton, J. A. ;

Le Jeune, I. R. ;

Hall, I. P. .

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2006, 99 (08) :505-511

[8] THE CORTICOTROPIN-RELEASING FACTOR FAMILY: PHYSIOLOGY OF THE STRESS RESPONSE [J].

Deussing, Jan M. ;

Chen, Alon .

PHYSIOLOGICAL REVIEWS, 2018, 98 (04) :2225-2286

[9] Herpes zoster ophthalmicus and syndrome of inappropriate antidiuretic hormone secretion [J].

Dhawan, Saurabh S. .

AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2007, 333 (01) :56-57

[10] The syndrome of inappropriate antidiuresis [J].

Ellison, David H. ;

Berl, Tomas .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (20) :2064-2072

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