Phytochemical screening and in vitro evaluation of antioxidant and antibacterial activity of aqueous and organic extracts of the Moroccan endemic medicinal plant Zygophyllum gaetulum

被引：0

作者：

Mammass, Bourassen ^{[1
]}

Rachid, Bouharroud ^{[2
]}

Lahbib, Fayzi ^{[1
]}

Mohammed, Hassi ^{[3
]}

Abdelhafed, Elasbahani ^{[4
]}

Mohamed, Alouani ^{[1
,5
]}

机构：

[1] Laboratory of Biotechnologies and Valorisation of Natural Resources, Faculty of Sciences, Ibn Zohr University, Agadir

[2] Regional Centre of Agricultural Research of Agadir, National Institute of Agricultural Research (INRA), Rabat

[3] Laboratory of Microbial Biotechnology and Plant Protection, Faculty of Sciences, Ibn Zohr University, Agadir

[4] Laboratory of Applied Chemistry and Environment, Faculty of Sciences, Ibn Zohr University, Agadir

[5] Faculty of Applied Sciences Ait Melloul, Ibn Zohr University, Agadir

来源：

International Journal of Environmental Studies | 2025年 / 82卷 / 01期

关键词：

antibacterial; Antioxidant; correlation analysis; phenolic; phytochemicals;

D O I：

10.1080/00207233.2025.2456447

中图分类号：

学科分类号：

摘要：

Zygophyllum gaetulum (Z. gaetulum), also known as Al Aggaya, is an endemic plant widespread in the Moroccan Sahara. This study aims to valorise Z. gaetulum from both phytochemical and pharmacological standpoints by extracting and quantifying total phenolic content (TPC) and total flavonoid content (TFC), assessing antioxidant activity through a series of in vitro tests, and evaluating antibacterial activity against four multidrug-resistant bacteria. The relationships between phytochemical content and antioxidant activity were also examined. The methanolic extract showed the highest levels of phenolic and flavonoid contents and the greatest antioxidant activity in both the DPPH and FRAP assays. But, no significant correlation was observed between TPC and the antioxidant activity assays. The antibacterial screening demonstrated that the 50% methanolic extract showed the largest inhibition zone against Escherichia coli. This study provides novel data and evidence that extracts from this plant are a promising source of natural antioxidants. © 2025 Informa UK Limited, trading as Taylor & Francis Group.

引用

页码：330 / 347

页数：17

共 69 条

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