Functional Status Trends for Adults and Children on Extracorporeal Membrane Oxygenation at Time of Lung Transplantation

被引：0

作者：

Wonshill Koh ^{[1
]}

JangDong Seo ^{[2
]}

Nicholas J. Ollberding ^{[1
]}

Don Hayes ^{[2
]}

机构：

[1] Cincinnati Children’s Hospital Medical Center,Heart Institute

[2] University of Cincinnati College of Medicine,Department of Pediatrics

[3] Cincinnati Children’s Hospital Medical Center,Division of Biostatistics and Epidemiology

[4] Cincinnati Children’s Hospital Medical Center,Division of Pulmonary Medicine

来源：

Lung | 2025年 / 203卷 / 1期

关键词：

Pediatric; Lung transplant; Functional status; ECMO;

D O I：

10.1007/s00408-025-00822-6

中图分类号：

学科分类号：

摘要：

Poor or worsening functional status of lung transplant (LTx) candidates is a key risk factor for waitlist and post-transplant mortality. As more critically ill adults and children are listed for LTx, the use of extracorporeal membrane oxygenation (ECMO) as bridge to LTx is also increasing. Sustaining optimal functional status while on the waitlist to LTx is crucial for LTx candidates as deterioration in functional status can negatively impact pre- and post-LTx outcomes. We conducted an analysis of the United Network for Organ Sharing Registry which showed that most patients (70%) on ECMO successfully bridged to LTx. The majority had severely limited functional status at the time of waitlisting but 96% of adults requiring ECMO on the waitlist for LTx either maintained or improved functional status from the time of waitlist to the time of LTx while all children on ECMO maintained or improved their functional status. With continuing medical and technical advances, the use of ECMO may also evolve to improve LTx candidates’ functional status.

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