CuratED: The emergency medicine pharmacotherapy literature of 2024

被引：0

作者：

Feldman, Ryan ^{[1
,2
]}

Faine, Brett ^{[3
]}

Rech, Megan A. ^{[4
]}

Zimmerman, David E. ^{[5
]}

Flack, Tara ^{[6
]}

Howington, Gavin T. ^{[7
,8
]}

Laub, Jessica ^{[9
]}

Porter, Blake ^{[10
]}

Slocum, Giles W. ^{[11
,12
]}

Zepeski, Anne ^{[3
]}

Santiago, Ruben D.

Woolum, Jordan ^{[7
,8
]}

Krenz, James

Sarangarm, Preeyaporn ^{[13
]}

Koehl, Jennifer ^{[14
]}

机构：

[1] Med Coll Wisconsin, Sch Pharm, Froedtert, Milwaukee, WI 53226 USA

[2] Med Coll Wisconsin, Dept Emergency Med, Div Med Toxicol, Milwaukee, WI 53226 USA

[3] Univ Iowa, Dept Emergency Med & Pharm Practice, Iowa City, IA 52242 USA

[4] Edward Hines Jr VA Hosp, Ctr Innovat Complex Chron Healthcare, Dept Vet Affairs, Hines, IL 60141 USA

[5] Univ Pittsburgh, Duquesne Univ, Mercy Hosp, Med Ctr,Sch Pharm, Room 311 Bayer Learning Ctr,600 Forbes Ave, Pittsburgh, PA 15282 USA

[6] IU Hlth Methodist Hosp, Dept Pharm, Indianapolis, IN 46202 USA

[7] Univ Kentucky, Coll Pharm, Dept Pharm Practice & Sci, Lexington, KY 40506 USA

[8] Univ Kentucky Healthcare, Dept Pharm Serv, Lexington, KY 40536 USA

[9] Ralph H Johnson VA Med Ctr, Dept Pharm, Charleston, SC 29412 USA

[10] Univ Vermont, Med Ctr, Dept Pharm, Burlington, VT 05401 USA

[11] Rush Univ, Med Ctr, Dept Emergency Med, Chicago, IL 60612 USA

[12] Rush Univ, Med Ctr, Dept Pharm, Chicago, IL 60612 USA

[13] Univ New Mexico Hosp, Dept Pharm, Albuquerque, NM 87106 USA

[14] Eli Lilly, Med Sci Liaison Gastroenterol, Denver, CO USA

来源：

AMERICAN JOURNAL OF EMERGENCY MEDICINE | 2025年 / 93卷

关键词：

Emergency medicine; Pharmacotherapy; Review; Literature; Clinical trial; CRITICALLY-ILL PATIENTS; POSITION STATEMENT; RESOURCE DOCUMENT; ISCHEMIC-STROKE; GUIDELINES; MANAGEMENT; UPDATE; TRAUMA; SAFETY;

D O I：

10.1016/j.ajem.2025.03.046

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The purpose of this article is to summarize pharmacotherapy related emergency medicine (EM) literature indexed in 2024. Articles were selected utilizing a modified Delphi approach. The table of contents from predetermined journals were reviewed and independently evaluated via the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system by paired authors. Pharmacotherapy-related publications deemed to be GRADE 1A and 1B were reviewed by the collective group for inclusion in the review. This article synthesizes and evaluates findings from 11 randomized controlled trials, 10 guidelines, clinical policies, position statements, or consensus recommendations, and 7 meta-analyses, providing critical insight into their potential clinical impact. Covered topics include guideline updates on seizure prophylaxis in traumatic brain injury, corticosteroid use in sepsis and acute respiratory distress and antibiotic prophylaxis in trauma. Additional topics include updates on thrombolytic therapy for acute ischemic stroke, including tenecteplase versus alteplase, anticoagulation reversal strategies with andexanet alpha and prothrombin complex concentrate, and the use of tranexamic acid in traumatic brain injury, ketamine versus etomidate for intubation in critically ill adults, expert consensus on heart failure hospitalization management, geriatric emergency medication safety recommendations, and emerging data on dual antiplatelet therapy for stroke management. (c) 2025 Published by Elsevier Inc.

引用

页码：146 / 153

页数：8