Synthesis and Characterization of New Acrylamide Derivatives and Studying Their Antibacterial Activity

被引：0

作者：

Dhedan, Ruaa M. ^{[1
]}

Awaad, Sana H. ^{[1
]}

Fadhl, Suha. N. ^{[1
]}

机构：

[1] Univ Baghdad, Coll Sci Women, Dept Chem, Baghdad, Iraq

来源：

BAGHDAD SCIENCE JOURNAL | 2025年 / 22卷 / 02期

关键词：

Acrylamide; Antibacterial activity; Heterocyclic compounds; Oxazepine; Schiff s bases; BIOLOGICAL-ACTIVITY;

D O I：

10.21123/bsj.2024.8556

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This study aims to test the new derivatives of polymers on the biological activities of two types of bacteria work describes the synthesis of 1,3-oxazepine and self-polymerization via a cycloaddition reaction between Schiff's bases 2-methyl-N-(5-(2-methylbutanoylimino) pentylidene)but-2-enamide and succinic, maleic anhydride. The synthesized compounds were characterized by melting points, softening points, and physical properties such as swelling capacity, TGA, and FT-IR. The biological activity showed intermediate results against two bacterial isolates resistant to antibiotics.

引用

页码：361 / 370

页数：11

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