Genomic and clinical-pathological features of mucinous cystadenocarcinoma of the breast with HER2 amplification: A case report

被引：0

作者：

Liu, Liling ^{[1
]}

Li, Mingxian ^{[1
]}

Qiu, Xinmin ^{[1
]}

Zheng, Xirun ^{[1
]}

Zheng, Guangjuan ^{[1
]}

Yang, Haifeng ^{[1
]}

机构：

[1] Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Pathol, 111 Dade Rd, Guangzhou 510120, Guangdong, Peoples R China

来源：

ONCOLOGY LETTERS | 2025年 / 29卷 / 06期

关键词：

breast; HER2; genomic features; mucinous cystadenocarcinoma; CANCER;

D O I：

10.3892/ol.2025.15050

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mucinous cystadenocarcinoma (MCA) of the breast is a rare, invasive carcinoma that resembles pancreatobiliary or ovarian MCA in terms of histological appearance. Most cases of MCA of the breast are negative for the estrogen receptor, progesterone receptor and ERBB2 (HER2). To the best of our knowledge, only five reports of HER2-positive MCA cases have been reported in the English language, and no reports focusing on the molecular characteristics of HER2-positive MCAs have been published. In the present study, a rare case of a 64-year-old woman with HER2-positive MCA who underwent long-term follow-up without recurrence or distant metastasis is reported. In addition, a detailed analysis of the genomic characteristics of the tumor is provided.

引用

页数：7

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