Low-dose oral minoxidil for frontal fibrosing alopecia: a 122-patient case series

被引：0

作者：

Pindado-Ortega, C. ^{[1
,2
]}

Pirmez, R. ^{[3
]}

Melo, D. F. ^{[4
]}

Binato, L. J. F. ^{[4
]}

Porrino-Bustamante, M. L. ^{[2
]}

Carpi, J. B. ^{[4
]}

Gil-Redondo, R. ^{[2
,5
]}

Hermosa-Gelbard, A. ^{[1
,2
]}

Jimenez-Cauhe, J. ^{[1
,2
]}

Saceda-Corralo, D. ^{[1
,2
]}

Vano-Galvan, S. ^{[1
,2
]}

机构：

[1] Univ Alcala, Hosp Univ Ramon & Cajal, IRYCIS, Dept Dermatol, Madrid, Spain

[2] Grp Dermatol Pedro Jaen, Unidad Tricol, Madrid, Spain

[3] Inst Dermatol Prof Rubem David Azulay, Dept Dermatol, St Casa Misericordia Rio Janeiro, Rio De Janeiro, Brazil

[4] Univ Estado Rio De Janeiro, UERJ, Dept Dermatol, Rio de Janeiro, Brazil

[5] Hosp Univ La Paz, Serv Dermatol, Madrid, Spain

来源：

ACTAS DERMO-SIFILIOGRAFICAS | 2025年 / 116卷 / 04期

关键词：

Alopecia; Minoxidil; Trichology; MULTICENTER; SAFETY;

D O I：

10.1016/j.ad.2024.05.029

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The objective of our study was to analyze the effectiveness of oral minoxidil on the frontotemporal hairline in patients with FFA. We conducted a retrospective, descriptive, multicenter study in 2 Brazilian and 1 Spanish centers. Responses were graded on a scale of 3 positive points. A total of 122 patients were included. Subjective improvement in the density of the frontotemporal hairline was observed in 45.1% patients, which was categorized as mild (34.4%), moderate (9.0%), and excellent (1.6%). Hair density improved in 57.4% of the patients' interparietal. Additionally, 25.4% and 3.3% of the patients experienced eyebrow and eyelash growth, respectively. Adverse effects were detected in 33.6% patients, with hypertrichosis being the most common (23.8%). In this study, oral minoxidil proved to be an additional therapy for FFA that not only improved the patients' overall hair and eyebrow growth, but also the density of the frontotemporal hairline. (c) 2024 AEDV. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

引用

页码：407 / 411

页数：5

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