Repurposing of epalrestat for neuroprotection in parkinson’s disease via activation of the KEAP1/Nrf2 pathway

被引：0
|
作者：
Huafang Jia [1 ]
Mengru Liu [1 ]
Hong Jiang [1 ]
Zhen Qiao [2 ]
Kaiyue Ren [2 ]
Xixun Du [1 ]
Xi Chen [1 ]
Qian Jiao [1 ]
Fengyuan Che [1 ]
机构：
[1] Qingdao Medical College,Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and State Key Disciplines, Physiology, School of Basic Medicine
[2] Qingdao University,Shandong Key Laboratory of Neurorehabilitation, School of Life Sciences and Health
[3] University of Health and Rehabilitation Sciences,Shandong Provincial Clinical Research Center for Geriatric Diseases; Key Laboratory of Neurophysiology, Health Commission of Shandong Province; Linyi Key Laboratory of Neurophysiology, Department of Neurolog
[4] Linyi People’s Hospital,undefined
来源：
Journal of Neuroinflammation | / 22卷 / 1期
关键词：
Epalrestat; Parkinson’s disease; KEAP1; Nrf2; Oxidative stress; Mitochondrial dysfunction;
D O I：
10.1186/s12974-025-03455-x
中图分类号：
学科分类号：
摘要：
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