Synthesis and Antibacterial Activity of Novel 1,2,3-Triazole Pendant 2-Styrylchromone Derivatives

被引：0

作者：

Limbadri, P. ^{[1
]}

Hemasri, Y. ^{[1
]}

Rao, Y. Jayaprakash ^{[2
]}

机构：

[1] Osmania Univ, Nizam Coll, Dept Chem, Hyderabad 500001, India

[2] Osmania Univ, Dept Chem, Hyderabad 500007, India

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2025年 / 95卷 / 04期

关键词：

hydroxystyrylchromone; propargyloxystyrylchromone; 1,3-dipolar cycloaddition; 1,2,3-triazoles; click chemistry; aryl azides; antibacterial activity; MICROWAVE-ASSISTED SYNTHESIS; ANTIMICROBIAL ACTIVITY; BIOLOGICAL EVALUATION; MOLECULAR DOCKING; REACTIVITY; AGENTS;

D O I：

10.1134/S1070363224610810

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new series of 1,2,3-triazole tethered 2-styrylchromone derivatives were synthesized by adopting a simple and efficient regioselective Cu(I) catalyzed 1,3-dipolar cycloaddition reaction of corresponding 3-O-propargyl 2-styrylchromone with various aryl azides. The synthesized compounds were characterized using H-1, C-13 NMR, HRMS and mass spectrometry and were screened for their antibacterial activity. Two representatives of synthesized dihalogen-substituted compounds showed good activity.

引用

页码：824 / 832

页数：9

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