Use of procalcitonin in therapeutic decisions in the pediatric intensive care unit

被引：1

作者：

Tissieres, Pierre ^{[1
]}

Torne, Elisabeth Esteban ^{[2
]}

Huebner, Johannes ^{[3
]}

Randolph, Adrienne G. ^{[4
]}

Galan, Corsino Rey ^{[5
]}

Weiss, Scott L. ^{[6
]}

机构：

[1] AP HP Paris Saclay Univ, Bicetre Hosp, IHU PROMETHEUS Comprehens Sepsis Ctr, Pediat Intens Care,Neonatal Med & Pediat Emergency, 78,Rue Gen Leclerc, F-94275 Le Kremlin Bicetre, France

[2] Univ Barcelona, Hosp Sant Joan Deu, Barcelona, Spain

[3] Ludwig Maximilians Univ Munchen, Hauner Childrens Hosp, Munich, Germany

[4] Boston Childrens Hosp, Dept Anesthesiol Crit Care & Pain Med, Boston, MA USA

[5] Univ Oviedo, Hosp Univ Cent Asturias HUCA, Hlth Res Inst Principal Asturias ISPA, Oviedo, Spain

[6] Thomas Jefferson Univ, Nemours Childrens Hlth, Jacksonville, DE USA

来源：

ANNALS OF INTENSIVE CARE | 2025年 / 15卷 / 01期

关键词：

Procalcitonin; Sepsis; Bacterial infections; Pediatric intensive care units; C-REACTIVE PROTEIN; CAMPAIGN INTERNATIONAL GUIDELINES; COMMUNITY-ACQUIRED PNEUMONIA; ANTIBIOTIC-TREATMENT; SERUM PROCALCITONIN; CARDIAC-ARREST; SEPTIC SHOCK; SEPSIS; CHILDREN; MARKER;

D O I：

10.1186/s13613-025-01470-y

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Procalcitonin (PCT) is frequently used by clinicians in children with suspected bacterial infections and sepsis. However interpretation in the critically ill child may be challenging due to the complexity of underlying conditions and its impact on PCT values. Herein, we propose a guidance for the use of procalcitonin in critically ill children, supported by a comprehensive analysis of the literature, to help the clinician for interpreting PCT in the various clinical conditions encountered in pediatric intensive care units. We describe the importance of the clinical context, timing of measurement and evidence on PCT values in diagnosing sepsis and to guide antibiotic therapy in critically ill children.

引用

页数：11

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