Crossing Age Boundaries: The Unifying Potential of Presepsin in Sepsis Diagnosis Across Diverse Age Groups

被引:0
作者
de Moura, Edmilson Leal Bastos [1 ,2 ]
Pereira, Rinaldo Wellerson [1 ,3 ]
机构
[1] Univ Brasilia UnB, Hlth Sci Doctoral Program, BR-70910900 Brasilia, DF, Brazil
[2] Dist Fed Univ UnDF, Sch Hlth Sci, BR-70710907 Brasilia, DF, Brazil
[3] Univ Catolica Brasilia, Genom Sci & Biotechnol Grad Program, BR-71966700 Brasilia, DF, Brazil
关键词
sepsis; biomarkers; presepsin; elderly; neonates; adults; PERSONALIZED MEDICINE; NEONATAL SEPSIS; GLOBAL BURDEN; ONSET SEPSIS; PROCALCITONIN; BIOMARKERS; MORTALITY; ACCURACY; SCD14-ST; HOSPITALIZATION;
D O I
10.3390/jcm13237038
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Sepsis is a pervasive condition that affects individuals of all ages, with significant social and economic consequences. The early diagnosis of sepsis is fundamental for establishing appropriate treatment and is based on warning scores and clinical characteristics, with positive microbiological cultures being the gold standard. Research has yet to identify a single biomarker to meet this diagnostic demand. Presepsin is a molecule that has the potential as a biomarker for diagnosing sepsis. In this paper, we present a narrative review of the diagnostic and prognostic performance of presepsin in different age groups. Given its particularities, it is identified that presepsin is a potential biomarker for sepsis at all stages of life.
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页数:16
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