Early administration of vitamin C in patients with sepsis or septic shock in emergency departments: a multicenter, double-blind, randomized controlled trial: the C-EASIE trial

被引：0

作者：

Stefanie Vandervelden ^{[1
]}

Bente Cortens ^{[1
]}

Steffen Fieuws ^{[2
]}

Wilma Eegdeman ^{[3
]}

Stefano Malinverni ^{[4
]}

Philippe Vanhove ^{[5
]}

Koen Monsieurs ^{[6
]}

Jan Breuls ^{[7
]}

Ives Hubloue ^{[8
]}

François Stifkens ^{[9
]}

Jacques Creteur ^{[10
]}

Lina Wauters ^{[3
]}

Didier Desruelles ^{[3
]}

机构：

[1] ZAS Augustinus,Department of Emergency Medicine

[2] Leuven Biostatistics and Statistical Bioinformatics Center (L-BioStat),Department of Emergency Medicine

[3] University Hospitals Leuven,Department of Emergency Medicine

[4] University Medical Center Saint Pierre,Department of Intensive Care

[5] ZAS Augustinus,Department of Emergency Medicine

[6] University Hospitals Antwerp,Department of Emergency Medicine

[7] Algemeen Ziekenhuis Turnhout,Department of Emergency Medicine

[8] University Hospitals Brussel,Department of Emergency Medicine

[9] Center Hospitalier Universitaire de Liège,Department of Intensive Care

[10] Erasme Hospital Brussels,undefined

来源：

Critical Care | / 29卷 / 1期

关键词：

Sepsis; Septic shock; Vitamin C; Ascorbic acid; C-EASIE;

D O I：

10.1186/s13054-025-05383-x

中图分类号：

学科分类号：

摘要：

Question Does early treatment with vitamin C lead to a less severe disease course in patients with sepsis or septic shock?

引用

共 50 条

[1] Early administration of Vitamin C in patients with sepsis or septic shock in emergency departments: A multicenter, double blinded, randomized controlled trial: The C-EASIE trial protocol
Vandervelden, Stefanie
Wauters, Lina
Breuls, Jan
Fieuws, Steffen
Vanhove, Philippe
Hubloue, Ives
Bartiaux, Magali
Creteur, Jacques
Stifkens, Francois
Monsieurs, Koen
Desruelles, Didier
PLOS ONE, 2021, 16 (11):
[2] Early administration of hydrocortisone, vitamin C, and thiamine in adult patients with septic shock: a randomized controlled clinical trial
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Zheng, Rui-Qiang
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Gu, Xiao-Hua
CRITICAL CARE, 2022, 26 (01)
[3] Early administration of hydrocortisone, vitamin C, and thiamine in adult patients with septic shock: a randomized controlled clinical trial
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Rui-Qiang Zheng
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Critical Care, 26
[4] Combination therapy of vitamin C and thiamine for septic shock in a multicentre, double-blind, randomized, controlled study (ATESS): study protocol for a randomized controlled trial
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[5] Combination therapy of vitamin C and thiamine for septic shock in a multicentre, double-blind, randomized, controlled study (ATESS): study protocol for a randomized controlled trial
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[6] Evaluating Vitamin C in Septic Shock: A Randomized Controlled Trial of Vitamin C Monotherapy*
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CRITICAL CARE MEDICINE, 2022, 50 (05) : E458 - E467
[7] Combined Treatment With Hydrocortisone, Vitamin C, and Thiamine for Sepsis and Septic Shock A Randomized Controlled Trial
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CHEST, 2020, 158 (01) : 174 - 182
[8] Intravenous Vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial
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[9] Intravenous Vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial
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[10] Intravenous vitamin C administration to patients with septic shock: a pilot randomised controlled trial
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