Current epidemiological status of mosquito-borne arboviruses in Gulf countries: a systematic review and meta-analysis

被引：0
作者：
Khalid Hajissa [1 ]
Mutiat Hammed-Akanmu [2 ]
Hussain Omar Alfaqih [3 ]
Ahmad A. Alshehri [4 ]
Mohammed Dauda Goni [5 ]
Maha Al-Asmakh [6 ]
机构：
[1] Department of Medical Microbiology and Immunology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain
[2] Department of Zoology, Faculty of Science and Technology, Omdurman Islamic University, Omdurman
[3] Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, Kota Baru, Kelantan, Pengkalan Chepa
[4] Department of Biomedicine, School of Health Sciences, Universiti Sains Malaysia, Kelantan, Kubang Kerian
[5] Faculty of Medicine, Cairo University, Al-Saray Street, El Manial, Cairo
[6] Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, P.O. Box 1988, Najran
[7] Department of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha
[8] Biomedical Research Center, Qatar University, Doha
来源：
Tropical Diseases, Travel Medicine and Vaccines | / 11卷 / 1期
关键词：
Arboviruses; Chikungunya; Dengue; Gulf countries; Mosquito-borne; Rift Valley fever; West Nile virus;
D O I：
10.1186/s40794-025-00247-2
中图分类号：
学科分类号：
摘要：
Background: Mosquito-borne viral (MBV) infections caused by dengue virus (DENV), Rift Valley fever virus (RVFV), West Nile virus (WNV), and chikungunya virus (CHIKV) pose a significant global public health concern. The aim of this systematic review is to summarise the reported prevalence data for these viruses in Gulf countries. Methods: A web search in four electronic databases (Scopus, PubMed, Google Scholar, and Web of Science) was conducted, and forty-four eligible studies were fulfilled the selection criteria and were therefore included in this study. The Pooled prevalence of MBVs was estimated using a random-effects model. The heterogeneity was assessed using Cochrane Q test and I2 test, while publication bias was evaluated using Egger’s test. Results: Using meta-analysis of proportions, the pooled prevalence of MBVs in Gulf countries among 34,367 human and 19,062 Animal samples was estimated to be 22.5% (95% CI: 13.7–31.4) and 11.6% (95% CI: 0.5 − 22.7%), respectively. In human, DENV was the most predominant virus reported in 19 studies, with an overall pooled prevalence of 32.4%, followed by RVFV in 9 studies, with an infection rate of 10.1%, while WNV and CHIKV were only reported in two studies, with overall prevalence rates of 6.4% and 2.4%, respectively. On the other hand, the overall prevalence of WNV and RVFV in animals was estimated to be 27.7% and 1.5%, respectively. Conclusion: This review revealed that MBVs are highly prevalent among humans in Gulf countries but relatively low in animals. As a result, additional therapeutic and preventive measures are required. However, the study highlights the need for further studies and surveillance to precisely monitor the burden of these viruses in the region. © The Author(s) 2025.
引用
收藏
相关论文
共 73 条
  • [1] Franklinos L.H., Et al., The effect of global change on mosquito-borne disease, Lancet Infect Dis, 19, 9, pp. e302-e312, (2019)
  • [2] Liu J., Et al., Insights into mosquito-borne arbovirus receptors, Cell Insight, (2024)
  • [3] Vega Rua A.J.O.I.C.-V., Okech, The Spread of Mosquito-Borne Diseases: A Major and Global Public Health Problem. Olfactory Concepts of Insect Control-Alternative to Insecticides, pp. 1-27, (2019)
  • [4] Poungou N., Et al., Mosquito-borne arboviruses occurrence and distribution in the last three decades in Central Africa: a systematic, Literature Rev, 12, 1, (2023)
  • [5] Pierson T.C., Diamond M., Continued Threat Emerg Flaviviruses, 5, 6, pp. 796-812, (2020)
  • [6] Madewell Z., Arboviruses Their Vectors, 113, 10, (2020)
  • [7] Daubney R., Hudson J., Enzootic hepatitis or Rift Valley fever. An un-described virus disease of sheep, cattle and man from East Africa, Journal of Pathology and Bacteriology, (1931)
  • [8] Himeidan Y.E., Et al., Recent outbreaks of rift valley fever in East Africa and the Middle East, Frontiers in public health, 2, (2014)
  • [9] Archer B.N., Epidemiologic investigations into outbreaks of Rift Valley fever in humans, Emerging Infectious Diseases, 19, 12, (2008)
  • [10] Efficacy trials of Rift Valley fever vaccines and therapeutics. Guidance on clinical trial design, World Health Organization Meeting Report, (2019)
12345678