A novel electrochemical sensor based on iron oxide nanoparticles coated with molecularly imprinted polymers for Bisphenol A detection

The widespread implementation of single-use products in modern society, driven by the demand for convenience, has raised concerns about potential hidden costs associated with their materials. Bisphenol A (BPA) has emerged as a ubiquitous synthetic phenolic compound primarily used as a building block in manufacturing polycarbonates (PC) and epoxy resins. Despite its pivotal role, concerns have been raised about BPA's potential health impact, primarily due to its potent endocrine-disrupting properties that can adversely affect bodily functions. For this reason, a novel electrochemical sensor for Bisphenol A detection has been developed, using a boron-doped diamond (BDD) electrode modified with iron oxide nanoparticles (MIP/Fe3O4 NPs) coated with a molecular imprinted polymer (MIP). Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR), and Dynamic Light Scattering (DLS) analysis confirmed the successful imprinting of BPA within the MIP. The sensor's electrochemical performance was assessed using differential pulse voltammetry (DPV). The results demonstrated a linear range of 5 to 73 mu M with an R2 value of 0.99 and a detection limit of 0.38 mu M. The sensor was reused four times and successfully utilized for detecting BPA in spiked water samples, foods, and beverages, offering results comparable to high-performance liquid chromatography.