Suicide by sodium nitrite: Autopsy case report

被引:0
作者
Jecmenica, Dragan [1 ]
Pavlekic, Snezana [1 ]
Zivkovic, Vladimir [1 ]
Repic, Aleksandra [1 ]
Markovic, Suzana [1 ]
Milosevic, Veljko [1 ]
机构
[1] Univ Belgrade, Inst Forens Med Milovan Milovanov, Sch Med, 31a Deligradska Str, Belgrade 11000, Serbia
关键词
Sodium nitrite; Poisoning; Methemoglobin; Suicide; Autopsy; NITRATE;
D O I
10.1016/j.legalmed.2025.102572
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Introduction: Suicide by sodium nitrite poisoning (SNP) is not common. In the last decade, an increase in the number of suicides caused by SNP was observed. Case report: A 47-year-old female was found dead in her apartment. Four cups with a yellowish liquid and a scale for precise measurement were found at the scene. Also, an empty plastic bag labeled " Sodium Nitrite NaNO2". In the external examination, general signs of asphyxia were noticed. Bluish and slightly brownish hypostasis, which was prominent on the face and thighs, was present. The blood and all tissues were somewhat darker in appearance than usual. Toxicological analysis showed high levels of nitrites, nitrates, methemoglobin, and metoclopramide in blood and stomach content. It was concluded that this was a suicide by SNP. Discussion: Autopsy signs of SNP are nonspecific. The grayish-brown color of the hypostasis is a characteristic sign of SNP but is very subjective and may be missed. Sodium nitrite cannot be legally purchased for domestic use in Serbia. Even though sodium nitrite commerce is strictly regulated, the victim was able to illegally obtain it and use it in combination with the antiemetic drug metoclopramide, which shows the knowledge that exceeds the common knowledge regarding this substance and is an example of suicide committed by intellectuals. Conclusion: Cases of the fatal SNP may present a significant challenge in forensic practice due to their rarity and nonspecific presentation. Without any information about the circumstances of the case, it is often unrecognizable.
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相关论文
共 30 条
[1]  
Alanazi MQ., 2017, J Hematol Thromboembolic Dis, V06, P5, DOI [10.4172/2329-8790.1000270, DOI 10.4172/2329-8790.1000270]
[2]   RETRACTED: Systematic Review of Fatal Sodium Nitrite Ingestion Cases: Toxicological and Forensic Implications (Retracted article) [J].
Albano, Giuseppe Davide ;
La Spina, Corinne ;
Buscemi, Roberto ;
Palmeri, Mattia ;
Malandrino, Giuliana ;
Licciardello, Fausto ;
Midiri, Mauro ;
Argo, Antonina ;
Zerbo, Stefania .
TOXICS, 2024, 12 (02)
[3]  
[Anonymous], 2021, Breast cancer: World Health Organization Internet
[4]   Four cases of sodium nitrite suicidal ingestion: A new trend and a relevant Forensic Pathology and Toxicology challenge [J].
Bugelli, V. ;
Tarozzi, I. ;
Manetti, Alice Chiara ;
Stefanelli, F. ;
Di Paolo, M. ;
Chericoni, S. .
LEGAL MEDICINE, 2022, 59
[5]   RAPID COLORIMETRIC DETERMINATION OF NITRATE IN PLANT-TISSUE BY NITRATION OF SALICYLIC-ACID [J].
CATALDO, DA ;
HAROON, M ;
SCHRADER, LE ;
YOUNGS, VL .
COMMUNICATIONS IN SOIL SCIENCE AND PLANT ANALYSIS, 1975, 6 (01) :71-80
[6]   Sodium nitrite food poisoning in one family [J].
Cvetkovic, Danica ;
Zivkovic, Vladimir ;
Lukic, Vera ;
Nikolic, Slobodan .
FORENSIC SCIENCE MEDICINE AND PATHOLOGY, 2019, 15 (01) :102-105
[7]   Fatal methemoglobinemia in three suicidal sodium nitrite poisonings [J].
Dean, Dorothy E. ;
Looman, Karen B. ;
Topmiller, Robert G. .
JOURNAL OF FORENSIC SCIENCES, 2021, 66 (04) :1570-1576
[8]   A fatal case by a suicide kit containing sodium nitrite ordered on the internet [J].
Durao, Carlos ;
Pedrosa, Frederico ;
Dinis-Oliveira, Ricardo Jorge .
JOURNAL OF FORENSIC AND LEGAL MEDICINE, 2020, 73
[9]  
Evelyn KA, 1938, J BIOL CHEM, V126, P655
[10]   ANALYSIS OF NITRATE, NITRITE, AND [N-15]-LABELED NITRATE IN BIOLOGICAL-FLUIDS [J].
GREEN, LC ;
WAGNER, DA ;
GLOGOWSKI, J ;
SKIPPER, PL ;
WISHNOK, JS ;
TANNENBAUM, SR .
ANALYTICAL BIOCHEMISTRY, 1982, 126 (01) :131-138