Intralesional Spesolimab: A Novel and Effective Approach for Palmoplantar Pustulosis Treatment - A Case Report

被引：0

作者：

Wang, Si-Ning ^{[1
]}

Lu, Yi-Zhou ^{[1
]}

Zhao, Yujuan ^{[1
]}

Cao, Wei ^{[1
]}

Zhang, Rui-Li ^{[1
]}

机构：

[1] Nanjing Med Univ, Affiliated Hosp 2, Dept Dermatol, Nanjing 210003, Peoples R China

来源：

INTERNATIONAL MEDICAL CASE REPORTS JOURNAL | 2025年 / 18卷

关键词：

Palmoplantar pustulosis; spesolimab; intralesional injection; case report;

D O I：

10.2147/IMCRJ.S503807

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Palmoplantar pustulosis (PPP) is a chronic condition characterized by the presence of sterile pustules on the palms and soles of the feet. As we all know, there is currently no gold standard for the treatment of this intractable disease. Currently, interleukin36 receptor (IL-36R)-targeted biologics are emerging as promising treatments for PPP. Here, we were the first to report a Chinese male with PPP who received an intralesional injection of spesolimab. We found that only a small intralesional injection volume of spesolimab could effectively suppress PPP in this case.

引用

页码：205 / 209

页数：5

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