A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy

被引：0

作者：

Zhang, Wei ^{[1
,2
]}

Fan, Yibao ^{[1
,2
,3
]}

Ashrafizadeh, Milad ^{[1
,2
]}

Shi, Dan ^{[1
,2
]}

Sethi, Gautam ^{[4
,5
]}

Ertas, Yavuz Nuri ^{[6
,7
]}

Abd El-Aty, A. M. ^{[8
,9
]}

Zhang, Xianbin ^{[1
,2
]}

Chen, Si ^{[10
]}

Gong, Peng ^{[1
,2
]}

机构：

[1] Shenzhen Univ, Gen Hosp, Inst Precis Diag & Treatment Digest Syst Tumors, Carson Int Canc Ctr,Dept Gen Surg, Shenzhen 518055, Guangdong, Peoples R China

[2] Shenzhen Univ, Gen Hosp, Carson Int Canc Ctr, Guangdong Prov Key Lab Chinese Med Ingredients & G, Shenzhen 518055, Guangdong, Peoples R China

[3] Shenzhen Univ, Med Sch, Sch Pharm, Shenzhen 518060, Guangdong, Peoples R China

[4] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Singapore 117600, Singapore

[5] Natl Univ Singapore, NUS Ctr Canc Res, Yong Loo Lin Sch Med, Singapore 117600, Singapore

[6] Erciyes Univ, Dept Biomed Engn, TR-38039 Kayseri, Turkiye

[7] Western Caspian Univ, Dept Tech Sci, AZ-1001 Baku, Azerbaijan

[8] Cairo Univ, Fac Vet Med, Dept Pharmacol, Giza 12211, Egypt

[9] Ataturk Univ, Med Fac, Dept Med Pharmacol, TR-25240 Erzurum, Turkiye

[10] Shenzhen Univ, Dept Immunol, Med Sch, Shenzhen 518060, Guangdong, Peoples R China

来源：

GENES & DISEASES | 2025年 / 12卷 / 03期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/j.gendis.2024.101503

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页数：4

共 5 条

[1] Stoffel E.M., Brand R.E., Goggins M., Pancreatic cancer: changing epidemiology and new approaches to risk assessment, early detection, and prevention, Gastroenterology, 164, 5, pp. 752-765, (2023)
[2] Zhang W., Fan Y., Zhang J., Et al., Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer, Drug Resist Updates, 71, (2023)
[3] Cai J., Chen H., Lu M., Et al., Advances in the epidemiology of pancreatic cancer: trends, risk factors, screening, and prognosis, Cancer Lett, 520, pp. 1-11, (2021)
[4] Huang X., Zhang G., Tang T.Y., Gao X., Liang T.B., Personalized pancreatic cancer therapy: from the perspective of mRNA vaccine, Mil Med Res, 9, 1, (2022)
[5] Cabasag C.J., Ferlay J., Laversanne M., Et al., Pancreatic cancer: an increasing global public health concern, Gut, 71, 8, pp. 1686-1687, (2022)

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