Vitamin K2 and the Vitamin-K-Cycle-Enzyme VKORC1L1 improve endothelial regeneration by inhibiting endothelial-mesenchymal transition, inflammatory cell activation and ferroptosis

被引：0
|
作者：
Al Zaidi, M. [1 ]
Repges, E. [1 ]
Tiyerili, V [1 ]
Oldenburg, J. [1 ]
Jansen, F. [1 ]
Nickenig, G. [1 ]
Zimmer, S. [1 ]
Aksoy, A. [1 ]
机构：
[1] Univ Hosp Bonn, Bonn, Germany
来源：
EUROPEAN HEART JOURNAL | 2024年 / 45卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：2
相关论文
共 21 条
  • [1] Vitamin K2 and the Vitamin-K-Cycle-Enzyme VKORC1L1 improve endothelial regeneration by inhibiting endothelial-mesenchymal transition, inflammatory cell activation and ferroptosis
    Al Zaidi, M.
    Repges, E.
    Tiyerili, V
    Oldenburg, J.
    Jansen, F.
    Nickenig, G.
    Zimmer, S.
    Aksoy, A.
    EUROPEAN HEART JOURNAL, 2024, 45
  • [2] The vitamin-k-cycle-enzyme VKORC1L1, but not its isoenzyme VKORC1, reduces inflammation in coronary endothelial cells
    Repges, E.
    Al Zaidi, M. A. Z.
    Jansen, F. J.
    Zimmer, S. Z.
    Tiyerlili, V. T.
    Nickenig, G. N.
    Aksoy, A. A.
    EUROPEAN HEART JOURNAL, 2023, 44
  • [3] Vitamin K inhibits ferroptosis via VKORC1L1
    Wang, Zhe
    NATURE CELL BIOLOGY, 2023, 25 (09) : 1240 - 1240
  • [4] Vitamin K inhibits ferroptosis via VKORC1L1
    Zhe Wang
    Nature Cell Biology, 2023, 25 : 1240 - 1240
  • [5] Four conserved cysteines of VKORC1L1 function in concert in the vitamin K cycle
    Tie, Jian-Ke
    Jin, Da-Yun
    Stafford, Darrel
    FASEB JOURNAL, 2014, 28 (01):
  • [6] VKORC1L1, An Enzyme Mediating the Effect of Vitamin K in Liver and Extrahepatic Tissues
    Lacombe, Julie
    Ferron, Mathieu
    NUTRIENTS, 2018, 10 (08):
  • [7] VKORC1 and VKORC1L1: Why do Vertebrates Have Two Vitamin K 2,3-Epoxide Reductases?
    Oldenburg, Johannes
    Watzka, Matthias
    Bevans, Carville G.
    NUTRIENTS, 2015, 7 (08): : 6250 - 6280
  • [8] Human Vitamin K 2,3-Epoxide Reductase Complex Subunit 1-like 1 (VKORC1L1) Mediates Vitamin K-dependent Intracellular Antioxidant Function
    Westhofen, Philipp
    Watzka, Matthias
    Marinova, Milka
    Hass, Moritz
    Kirfel, Gregor
    Mueller, Jens
    Bevans, Carville G.
    Mueller, Clemens R.
    Oldenburg, Johannes
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (17) : 15085 - 15094
  • [9] VKORC1L1, an Enzyme Rescuing the Vitamin K 2,3-Epoxide Reductase Activity in Some Extrahepatic Tissues during Anticoagulation Therapy
    Hammed, Abdessalem
    Matagrin, Benjamin
    Spohn, Gabriele
    Prouillac, Caroline
    Benoit, Etienne
    Lattard, Virginie
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (40) : 28733 - 28742
  • [10] UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development
    Hegarty, Jeffrey M.
    Yang, Hongbo
    Chi, Neil C.
    DEVELOPMENT, 2013, 140 (08): : 1713 - 1719
123