Exploring stem cell technology: Pioneering new pathways for female fertility preservation and restoration

被引:2
作者
Li, Ningjing [1 ]
Du, Xinrong [1 ]
Zhao, Yuhong [3 ]
Zeng, Qin [2 ]
Han, Changli [1 ]
Xiong, Dongsheng [2 ]
He, Libing [2 ]
Zhang, Guohui [2 ]
Liu, Weixin [2 ]
机构
[1] Chengdu Univ Tradit Chinese Med, Sch Med & life Sci, Chengdu 611137, Peoples R China
[2] Chengdu Med Coll, Sichuan Prov Womans & Childrens Hosp, Affiliated Womens & Childrens Hosp, Chengdu 610045, Peoples R China
[3] Chengdu Med Coll, Coll Lab Med, Chengdu 610500, Peoples R China
关键词
Female fertility preservation; Stem cells; Ovarian tissue cryopreservation; in vitro culture of ovarian tissue; Ovarian organoids; CANCER; TISSUE; OOCYTES; WOMEN; CRYOPRESERVATION; TRANSPLANTATION; VITRIFICATION; CHEMOTHERAPY; ORGANOIDS; OPTIONS;
D O I
10.1016/j.repbio.2024.100958
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The fertility of women is crucial for the well-being of individuals and families. However, various factors such as chemotherapy, lifestyle changes, among others, may lead to a decline in female fertility, thus emphasizing the significance of preserving and restoring fertility. Stem cells, with their unique capacity for self-renewal and pluripotent differentiation, have made significant strides in areas such as ovarian tissue cryopreservation, in vitro culture of frozen-thawed ovarian tissue, and construction of ovarian-like organs. This review aims to summarize the latest findings in these fields, highlighting the pivotal role, mechanisms, and future prospects of stem cell technology in preserving and restoring female fertility. Additionally, the importance of interdisciplinary collaboration is underscored, as personalized stem cell therapy regimens tailored through interdisciplinary cooperation between reproductive medicine and stem cell fields hold promise in providing reliable solutions for the preservation and restoration of female fertility.
引用
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页数:12
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