Central Nervous System Manifestations of Graft-Versus-Host Disease

被引：0

作者：

Desai, Nihar ^{[1
,2
]}

Khaire, Niranjan ^{[1
]}

Cyriac, Sunu ^{[1
,3
]}

Alrumeh, Aseem Saleh ^{[4
]}

Diamandis, Phedias ^{[4
]}

Mandell, Daniel M. ^{[5
,6
]}

Moya, Tommy Alfaro ^{[1
,2
]}

Al-Shaibani, Eshrak ^{[1
,2
]}

Novitzky-Basso, Igor ^{[1
,2
]}

Pasic, Ivan ^{[1
,2
]}

Law, Arjun Datt ^{[1
,2
]}

Michelis, Fotios V. ^{[1
,2
]}

Kumar, Rajat ^{[1
,2
]}

Kim, Dennis Dong Hwan ^{[1
,2
]}

Mattsson, Jonas ^{[1
,2
]}

Viswabandya, Auro ^{[1
,2
]}

机构：

[1] Princess Margaret Canc Ctr, Hans Messner Allogene Blood & Marrow Transplant Pr, Div Med Oncol & Hematol, Toronto, ON, Canada

[2] Univ Toronto, Temerty Fac Med, Toronto, ON, Canada

[3] Amala Inst Med Sci, Trichur, Kerala, India

[4] Princess Margaret Canc Ctr, Dept Lab Med & Pathobiol, Toronto, ON, Canada

[5] Univ Hlth Network, Dept Med Imaging, Toronto, ON, Canada

[6] Univ Toronto, Toronto, ON, Canada

来源：

EUROPEAN JOURNAL OF HAEMATOLOGY | 2025年 / 115卷 / 01期

关键词：

central nervous system; graft-versus-host disease; hematopoietic stem cell transplantation; immunosuppressive therapy; neurological complications;

D O I：

10.1111/ejh.14416

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：96 / 98

页数：3

共 9 条

[1] Donor bone marrow-derived macrophage MHC II drives neuroinflammation and altered behavior during chronic GVHD in mice [J].

Adams, Rachael C. ;

Carter-Cusack, Dylan ;

Shaikh, Samreen N. ;

Llanes, Genesis T. ;

Johnston, Rebecca L. ;

Quaife-Ryan, Gregory ;

Boyle, Glen ;

Koufariotis, Lambros T. ;

Moller, Andreas ;

Blazar, Bruce R. ;

Vukovic, Jana ;

MacDonald, Kelli P. A. .

BLOOD, 2022, 139 (09) :1389-1408

[2] PTCy-based graft-versus-host disease prophylaxis for matched sibling donor allogeneic hematopoietic cell transplantation [J].

Desai, Nihar ;

Altareb, Majed ;

Remberger, Mats ;

Chen, Carol ;

Moya, Tommy Alfaro ;

Al-Shaibani, Eshrak ;

Novitzky-Basso, Igor ;

Pasic, Ivan ;

Lam, Wilson ;

Michelis, Fotios, V ;

Gerbitz, Armin ;

Viswabandya, Auro ;

Kumar, Rajat ;

Kim, Dennis Dong Hwan ;

Lipton, Jeffrey H. ;

Mattsson, Jonas ;

Law, Arjun Datt .

BLOOD ADVANCES, 2025, 9 (03) :660-669

[3] Neurological manifestations of chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: report from the Consensus Conference on Clinical Practice in chronic graft-versus-host disease [J].

Grauer, Oliver ;

Wolff, Daniel ;

Bertz, Hartmut ;

Greinix, Hildegard ;

Kuehl, Joern-Sven ;

Lawitschka, Anita ;

Lee, Stephanie J. ;

Pavletic, Steven Z. ;

Holler, Ernst ;

Kleiter, Ingo .

BRAIN, 2010, 133 :2852-2865

[4] The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model [J].

Haile, Woldeab B. ;

Gavegnano, Christina ;

Tao, Sijia ;

Jiang, Yong ;

Schinazi, Raymond F. ;

Tyor, William R. .

NEUROBIOLOGY OF DISEASE, 2016, 92 :137-143

[5]

Lambert N., 2024, BRAIN J NEUROLOGY, pawa

[6] Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia [J].

Mathew, Nimitha R. ;

Vinnakota, Janaki M. ;

Apostolova, Petya ;

Erny, Daniel ;

Hamarsheh, Shaimaa ;

Andrieux, Geoffroy ;

Kim, Jung-Seok ;

Hanke, Kathrin ;

Goldmann, Tobias ;

Chappell-Maor, Louise ;

El-Khawanky, Nadia ;

Ihorst, Gabriele ;

Schmidt, Dominik ;

Duyster, Justus ;

Finke, Jurgen ;

Blank, Thomas ;

Boerries, Melanie ;

Blazar, Bruce R. ;

Jung, Steffen ;

Prinz, Marco ;

Zeiser, Robert .

JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (03) :1315-1329

[7] Case report: Central nervous system involvement of human graft versus host disease: Report of 7 cases and a review of literature [J].

Ruggiu, Mathilde ;

Cuccuini, Wendy ;

Mokhtari, Karima ;

Meignin, Veronique ;

de Latour, Regis Peffault ;

Robin, Marie ;

de Fontbrune, Flore Sicre ;

Xhaard, Alienor ;

Socie, Gerard ;

Michonneau, David .

MEDICINE, 2017, 96 (42)

[8] Neurological adverse events post allogeneic hematopoietic cell transplantation: major determinants of morbidity and mortality [J].

Sakellari, Ioanna ;

Gavriilaki, Eleni ;

Papagiannopoulos, Sotirios ;

Gavriilaki, Maria ;

Batsis, Ioannis ;

Mallouri, Despina ;

Vardi, Anna ;

Constantinou, Varnavas ;

Masmanidou, Marianna ;

Yannaki, Evangelia ;

Smias, Christos ;

Geroukis, Triantafyllos ;

Kazis, Dimitrios ;

Kimiskidis, Vasileios ;

Anagnostopoulos, Achilles .

JOURNAL OF NEUROLOGY, 2019, 266 (08) :1960-1972

[9] First use of ibrutinib for the treatment of post-transplant central nervous system graft-versus-host disease [J].

Trando, Aaron ;

Dunn-Pirio, Anastasie ;

Koura, Divya ;

Goodman, Aaron M. .

BRITISH JOURNAL OF HAEMATOLOGY, 2023,

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