Feasibility, Acceptability, and Preliminary Efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents in China: A Pilot Study

Currently, there is a lack of cost-effective and accessible intervention resources for Chinese adolescents with emotional disorders. The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A), which aims to apply transdiagnostic treatment principles to target core dysfunctions across a range of emotional disorders with a single protocol, could fill this gap. We first modified the UP-A for use in the Chinese cultural context and then assessed its feasibility, acceptability, and preliminary efficacy using a single-arm design. Twenty-four Chinese adolescents (14.1 +/- 1.2 years old) with emotional disorders completed a 12-week group UP-A intervention along with their parents. Multiple outcomes were evaluated at five time points: pretreatment (T1), week 4 (T2), week 8 (T3), posttreatment (T4), and 3-month follow-up (T5). The results showed a low dropout rate (16.7%), high attendance (at 10.2 +/- 1.6 sessions in adolescents and 10.7 +/- 2.0 sessions in parents), and sufficient participant satisfaction. Adolescents exhibited significant decreases in emotional disorder severity (g =-1.298 to-1.341) and emotional symptoms (g =-0.440 to-1.988) and significant improvements in emotion regulation (ER) strategies, resilience, functional outcomes, and executive function. The efficacy of the intervention was significant starting at T2 and was maintained at T4 and T5. Exploratory analyses revealed that predictors of treatment outcomes included the presence of multiple comorbidities, the severity of emotional disorders, adaptive ER strategies, and resilience at T1. This study demonstrated the feasibility, acceptability, and preliminary efficacy of the Chinese version of the UP-A, and future randomized controlled trials are warranted.