Health-Related Quality of Life After Colorectal Cancer Surgery in Older Patients Compared to the Young: A Prospective Multicentre Observational Study

被引：0

作者：

Pang, Ning Qi ^{[1
,2
]}

Lau, Jerrald ^{[3
,4
]}

Tan, Ker-Kan ^{[3
,4
,5
]}

Singapore Colorectal Canc Res Grp

Peh, Cherie Hui ^{[4
]}

Ng, Alyssa Isabelle ^{[4
]}

Koh, Wei-Ling ^{[4
]}

Choe, Lina ^{[3
]}

Lieske, Bettina ^{[5
]}

Cheong, Wai-Kit ^{[5
]}

Ng, Jing-Yu ^{[5
]}

Chan, Dedrick Kok Hong ^{[4
,5
]}

Tan, Ian Jse-Wei ^{[5
]}

Lee, Kai-Yin ^{[5
]}

Buan, Bryan Jun-Liang ^{[5
]}

Tan, Jarrod Kah-Hwee ^{[5
]}

Seow, Choon-Sheong ^{[6
]}

Keh, Christopher Hang-Liang ^{[6
]}

Ngu, James Chi-Yong ^{[7
]}

Lim, Kok-Ren ^{[7
]}

Chew, Min-Hoe ^{[8
]}

Foo, Fung-Joon ^{[8
]}

Koh, Frederick ^{[8
]}

Sivarajah, Sharmini Su ^{[8
]}

Lee, Daniel ^{[9
]}

Tan, Kok-Yang ^{[9
]}

机构：

[1] Natl Univ Hlth Syst, Natl Univ Hosp, Dept Surg, Div Hepatobiliary & Pancreat Surg, Singapore, Singapore

[2] Natl Univ Hlth Syst, Natl Univ Ctr Organ Transplantat NUCOT, Natl Univ Hosp, Singapore, Singapore

[3] Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore

[4] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore

[5] Natl Univ Hlth Syst, Natl Univ Hosp, Dept Surg, Div Colorectal Surg, Singapore, Singapore

[6] Ng Teng Fong Gen Hosp, Dept Gen Surg, Singapore, Singapore

[7] Changi Gen Hosp, Dept Surg, Singapore, Singapore

[8] Sengkang Gen Hosp, Dept Gen Surg, Singapore, Singapore

[9] Khoo Teck Puat Hosp, Dept Surg, Singapore, Singapore

来源：

JOURNAL OF APPLIED GERONTOLOGY | 2025年

基金：

英国医学研究理事会;

关键词：

quality of life; cancer; health-related quality of life; older adults; peri-operative care; ELDERLY-PATIENTS; CLINICAL-TRIALS; QLQ-C30;

D O I：

10.1177/07334648251321560

中图分类号：

R4 [临床医学]; R592 [老年病学];

学科分类号：

1002 ; 100203 ; 100602 ;

摘要：

Introduction: The impact of colorectal surgery on older adults' (>= 65 years) health-related quality of life (HRQoL) is rarely reported. Methods: This prospective multi-institutional cohort study involving 217 participants investigated factors affecting older colorectal cancer (CRC) patients' HRQoL following surgery with the EORTC QLQ-C30 and the HADS. Results: The trend of the global QoL and individual subscales show an overall dip in QoL from baseline to pre-discharge, before slowly rising until the 6-month mark. Baseline score of individual outcome measures was the only constant predictor of the outcome measure over time. Conclusion: Age was not found to be a significant predictor of HRQoL in older adults undergoing colorectal surgery, while baseline scores of individual outcome measures consistently predicted post-operative HRQoL scores. Interventions should be targeted at specific subgroups of older adults scheduled for colorectal surgery, such as those with lower baseline scores.

引用

页数：10

共 50 条

[31] Assessment of health-related quality of life in Thai patients after heart surgery
Sakthong, Phantipa
Kasemsup, Vijj
Winit-Watjana, Win
ASIAN BIOMEDICINE, 2015, 9 (02) : 203 - 210
[32] A causal model of health-related quality of life in colorectal cancer patients post-surgery
Tran, Thi Hong Hanh
Thanasilp, Sureeporn
Pudtong, Noppamat
EUROPEAN JOURNAL OF ONCOLOGY NURSING, 2024, 72
[33] Determining clinically important differences in health-related quality of life in older patients with cancer undergoing chemotherapy or surgery
Quinten, C.
Kenis, C.
Decoster, L.
Debruyne, P. R.
De Groof, I.
Focan, C.
Cornelis, F.
Verschaeve, V.
Bachmann, C.
Bron, D.
Luce, S.
Debugne, G.
Van den Bulck, H.
Goeminne, J. C.
Baitar, A.
Geboers, K.
Petit, B.
Langenaeken, C.
Van Rijswijk, R.
Specenier, P.
Jerusalem, G.
Praet, J. P.
Vandenborre, K.
Lycke, M.
Flamaing, J.
Milisen, K.
Lobelle, J. P.
Wildiers, H.
QUALITY OF LIFE RESEARCH, 2019, 28 (03) : 663 - 676
[34] Surgery and health-related quality of life-A prospective follow up study on breast cancer patients in Finland
Rautalin, Mervi
Jahkola, Tiina
Roine, Risto P.
EJSO, 2021, 47 (07): : 1581 - 1587
[35] Patient-reported health-related quality of life after colorectal surgery
Kuzmanovska, Biljana
Kuzmanovski, Igor
Jankulovski, Nikola
Kartalov, Andrijan
Bujar, Osmani
Jovanovski-Srceva, Marija
Brzanov, Nikola
Gavrilovska-Brzanov, Aleksandra
POLISH JOURNAL OF SURGERY, 2020, 94 (04) : 20 - 26
[36] A Prospective Study Evaluating Health-Related Quality of Life Following a Multimodal Treatment for Colorectal Cancer
Perrone, Maria
Garufi, Carlo
Cosimelli, Maurizio
Graziano, Franco
Falcicchio, Chiara
Bonucci, Alessandro
Fotia, Luana
Giannarelli, Diana
Giacomelli, Luca
Ciliberto, Gennaro
Pugliese, Patrizia
JOURNAL OF GASTROINTESTINAL CANCER, 2023, 54 (01) : 117 - 125
[37] Changes in health-related quality of life in older women after diagnosis with gynecologic cancer
Klapheke, Amy K.
Keegan, Theresa H. M.
Ruskin, Rachel
Cress, Rosemary D.
GYNECOLOGIC ONCOLOGY, 2020, 156 (02) : 475 - 481
[38] Health-related quality of life, anxiety and depression among adolescents and young adults with cancer:: A prospective longitudinal study
Jorngarden, Anna
Mattsson, Elisabet
von Essen, Louise
EUROPEAN JOURNAL OF CANCER, 2007, 43 (13) : 1952 - 1958
[39] Health-related quality of life of colorectal cancer patients receiving oral UFT plus leucovorin compared with those with surgery alone
Akira Tsunoda
Kentaro Nakao
Yuko Tsunoda
Makoto Watanabe
Nobuaki Matsui
International Journal of Clinical Oncology, 2010, 15 : 153 - 160
[40] Patient-reported health-related quality of life after colorectal surgery
Kuzmanovska, Biljana
Kuzmanovski, Igor
Jankulovski, Nikola
Kartalov, Andrijan
Bujar, Osmani
Jovanovski-Srceva, Marija
Brzanov, Nikola
Gavrilovska-Brzanov, Aleksandra
POLISH JOURNAL OF SURGERY, 2022, 94 (04) : 20 - 25

← 1 2 3 4 5 →