Health-Related Quality of Life After Colorectal Cancer Surgery in Older Patients Compared to the Young: A Prospective Multicentre Observational Study

被引：0

作者：

Pang, Ning Qi ^{[1
,2
]}

Lau, Jerrald ^{[3
,4
]}

Tan, Ker-Kan ^{[3
,4
,5
]}

Singapore Colorectal Canc Res Grp

Peh, Cherie Hui ^{[4
]}

Ng, Alyssa Isabelle ^{[4
]}

Koh, Wei-Ling ^{[4
]}

Choe, Lina ^{[3
]}

Lieske, Bettina ^{[5
]}

Cheong, Wai-Kit ^{[5
]}

Ng, Jing-Yu ^{[5
]}

Chan, Dedrick Kok Hong ^{[4
,5
]}

Tan, Ian Jse-Wei ^{[5
]}

Lee, Kai-Yin ^{[5
]}

Buan, Bryan Jun-Liang ^{[5
]}

Tan, Jarrod Kah-Hwee ^{[5
]}

Seow, Choon-Sheong ^{[6
]}

Keh, Christopher Hang-Liang ^{[6
]}

Ngu, James Chi-Yong ^{[7
]}

Lim, Kok-Ren ^{[7
]}

Chew, Min-Hoe ^{[8
]}

Foo, Fung-Joon ^{[8
]}

Koh, Frederick ^{[8
]}

Sivarajah, Sharmini Su ^{[8
]}

Lee, Daniel ^{[9
]}

Tan, Kok-Yang ^{[9
]}

机构：

[1] Natl Univ Hlth Syst, Natl Univ Hosp, Dept Surg, Div Hepatobiliary & Pancreat Surg, Singapore, Singapore

[2] Natl Univ Hlth Syst, Natl Univ Ctr Organ Transplantat NUCOT, Natl Univ Hosp, Singapore, Singapore

[3] Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore

[4] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore

[5] Natl Univ Hlth Syst, Natl Univ Hosp, Dept Surg, Div Colorectal Surg, Singapore, Singapore

[6] Ng Teng Fong Gen Hosp, Dept Gen Surg, Singapore, Singapore

[7] Changi Gen Hosp, Dept Surg, Singapore, Singapore

[8] Sengkang Gen Hosp, Dept Gen Surg, Singapore, Singapore

[9] Khoo Teck Puat Hosp, Dept Surg, Singapore, Singapore

来源：

JOURNAL OF APPLIED GERONTOLOGY | 2025年

基金：

英国医学研究理事会;

关键词：

quality of life; cancer; health-related quality of life; older adults; peri-operative care; ELDERLY-PATIENTS; CLINICAL-TRIALS; QLQ-C30;

D O I：

10.1177/07334648251321560

中图分类号：

R4 [临床医学]; R592 [老年病学];

学科分类号：

1002 ; 100203 ; 100602 ;

摘要：

Introduction: The impact of colorectal surgery on older adults' (>= 65 years) health-related quality of life (HRQoL) is rarely reported. Methods: This prospective multi-institutional cohort study involving 217 participants investigated factors affecting older colorectal cancer (CRC) patients' HRQoL following surgery with the EORTC QLQ-C30 and the HADS. Results: The trend of the global QoL and individual subscales show an overall dip in QoL from baseline to pre-discharge, before slowly rising until the 6-month mark. Baseline score of individual outcome measures was the only constant predictor of the outcome measure over time. Conclusion: Age was not found to be a significant predictor of HRQoL in older adults undergoing colorectal surgery, while baseline scores of individual outcome measures consistently predicted post-operative HRQoL scores. Interventions should be targeted at specific subgroups of older adults scheduled for colorectal surgery, such as those with lower baseline scores.

引用

页数：10

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