The Efficacy and Safety of Homoharringtonine Added to Venetoclax and Azacitidine in the Frontline Treatment of Newly Diagnosed Acute Myeloid Leukemia, a Multi-Center Exploratory Cohort Study

被引：0
|
作者：
Yu, Guopan [1 ]
Yao, Zurong [1 ]
Yin, Zhao [1 ]
Zhang, Yu [1 ]
Zhao, Weihua [2 ]
Weng, Guangyang [3 ]
Guo, Ziwen [4 ]
Sun, Zhiqiang [5 ]
Shi, Pengcheng [1 ]
Jiang, Xuejie [6 ]
Xu, Dan [1 ]
Xuan, Li [1 ]
Liu, Qifa [1 ]
机构：
[1] Southern Med Univ, Nanfang Hosp, Dept Hematol, Guangzhou, Peoples R China
[2] Guangxi Med Univ, Affiliated Hosp 1, Dept Hematol, Nanning, Peoples R China
[3] Shenzhen Second Peoples Hosp, Dept Hematol, Shenzhen, Peoples R China
[4] Zhongshan City Peoples Hosp, Dept Hematol, Zhongshan, Peoples R China
[5] Southern Med Univ, Shenzhen Hosp, Dept Hematol, Shenzhen, Peoples R China
[6] Guangzhou Med Univ, Affiliated Hosp 2, Dept Hematol, Guangzhou, Peoples R China
来源：
BLOOD | 2024年 / 144卷
关键词：
homoharringtonine; venetoclax/azacitidine; acute myeloid leukemia; efficacy; safety;
D O I：
10.1182/blood-2024-206872
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：4283 / 4283
页数：1
相关论文
共 50 条
  • [1] Homoharringtonine Overcomes the Negative Impact of Genetic Patterns on Venetoclax Plus Azacitidine Regimen in Relapsed/Refractory Acute Myeloid Leukemia: A Multi-Center, Cohort Study
    Yu, Guopan
    Zhang, Yu
    Jin, Hua
    Yin, Zhao
    Weng, Guangyang
    Yu, Sijian
    Xu, Na
    Du, Xin
    Lin, Dongjun
    Xiao, Jie
    Sun, Zhiqiang
    Zhang, Hongyu
    Liang, Xinquan
    Guo, Ziwen
    Zhao, Weihua
    Dai, Min
    Jiang, Xuejie
    Xuan, Li
    Shi, Pengcheng
    BLOOD, 2023, 142
  • [2] Azacitidine Plus Venetoclax for the Treatment of Relapsed and Newly Diagnosed Acute Myeloid Leukemia Patients
    Garciaz, Sylvain
    Hospital, Marie-Anne
    Alary, Anne-Sophie
    Saillard, Colombe
    Hicheri, Yosr
    Mohty, Bilal
    Rey, Jerome
    D'Incan, Evelyne
    Charbonnier, Aude
    Villetard, Ferdinand
    Maisano, Valerio
    Lombardi, Laura
    Ittel, Antoine
    Mozziconacci, Marie-Joelle
    Gelsi-Boyer, Veronique
    Vey, Norbert
    CANCERS, 2022, 14 (08)
  • [3] Combining azole antifungals with venetoclax plus azacitidine in patients with newly diagnosed acute myeloid leukemia
    Zhong, Xushu
    Wang, Jia
    Dai, Yang
    Huang, Xiaoou
    Liu, Jiazhuo
    Xiang, Bing
    Ma, Hongbing
    HEMATOLOGY, 2024, 29 (01)
  • [4] Azacitidine and venetoclax with or without pevonedistat in patients with newly diagnosed acute myeloid leukemia
    Short, Nicholas J.
    Wierzbowska, Agnieszka
    Cluzeau, Thomas
    Laribi, Kamel
    Recher, Christian
    Czyz, Jaroslaw
    Ochrem, Bogdan
    Ades, Lionel
    Gallego-Hernanz, Maria Pilar
    Heiblig, Mael
    Audisio, Ernesta
    Zarzycka, Ewa
    Li, Shuli
    Ferenc, Nicholas
    Yeh, Tammie
    Faller, Douglas V.
    Sedarati, Farhad
    Papayannidis, Cristina
    LEUKEMIA & LYMPHOMA, 2025, 66 (03) : 458 - 468
  • [5] Single-center experience of venetoclax combined with azacitidine in young patients with newly diagnosed acute myeloid leukemia
    Xu, Xuezhu
    Liu, Rui
    Chen, Hongli
    Yang, Ruoyu
    Gao, Gongzhizi
    He, Aili
    Wang, Fangxia
    THERAPEUTIC ADVANCES IN HEMATOLOGY, 2025, 16
  • [6] Treatment Response and Impact Factor of Venetoclax Based Regimens in the Frontline Treatment of Newly Diagnosed Unfit Acute Myeloid Leukemia in the Real World of China
    Yu, Guopan
    Yin, Zhao
    Xu, Dan
    Jiang, Xuejie
    Ye, Jieyu
    Zhang, Yu
    BLOOD, 2022, 140 : 11740 - 11740
  • [7] Efficacy and safety of cladribine, low-dose cytarabine and venetoclax in newly diagnosed and relapsed/refractory acute myeloid leukemia: results of a single center study
    Ting Zhu
    Li Wang
    Hui Jiang
    Shujuan Huang
    Haitao Xu
    Anyou Wang
    Xin Liu
    Annals of Hematology, 2025, 104 (5) : 2745 - 2753
  • [8] Efficacy and safety of venetoclax and azacitidine for acute myeloid leukemia in China: a real-world single-center study
    Jie-Fei Bai
    Ting Wang
    Jiang-Tao Li
    Chun-Li Zhang
    Long Qian
    Ya-Zi Yang
    Xiao-Ya Yun
    Jing-Jing Yin
    Fei Zhao
    Wei-Dong Ding
    Bao-Li Xing
    Shang-Yong Ning
    Lei Pei
    Xiao-Dong Xu
    Hui Liu
    Ru Feng
    BMC Cancer, 25 (1)
  • [9] Venetoclax in Combination with Azacitidine for the Treatment of Newly Diagnosed Acute Myeloid Leukemia: A Canadian Cost-Utility Analysis
    Guinan, Kimberly
    Mathurin, Karine
    Au, Yunghan
    Schuh, Andre C.
    Bui, Cat N.
    Chai, Xinglei
    Lachaine, Jean
    CURRENT ONCOLOGY, 2022, 29 (10) : 7524 - 7536
  • [10] Combination of Homoharringtonine with Venetoclax and Azacitidine Excerts Better Treatment Response in Relapsed/Refractory Acute Myeloid Leukemia
    Yu, Guopan
    Xu, Na
    Huang, Fen
    Fan, Zhiping
    Liu, Hui
    Shi, Pengcheng
    Zhou, Hongsheng
    Wang, Zhixiang
    Zhang, Yu
    Liu, Qifa
    BLOOD, 2020, 136
12345