DEVELOPMENT OF EX VIVO PATIENT-DERIVED MODELS TO UNCOVER THE TUMOR-IMMUNE MICROENVIRONMENT IN RENAL CELL CARCINOMA

被引：0
|
作者：
Soki, Kashima [1 ]
Ruchi, Gupta [1 ]
Vivien, Moritz [1 ]
Katherine, Sadak [1 ]
Julia, Walker [1 ]
Adebowale, Adeniran [1 ]
Peter, Humphrey [1 ]
Daniel, Dinulescu [1 ]
Doug, Palmer [1 ]
Scott, Hammond [1 ]
Marcus, Bosenberg [1 ]
Michael, Hurwitz [1 ]
Patrick, Kenney [1 ]
David, A. Braun [1 ]
机构：
[1] Yale Canc Ctr, Yale Sch Med, New Haven, CT 06510 USA
来源：
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS | 2025年 / 43卷 / 03期
关键词：
D O I：
10.1016/j.urolonc.2024.12.057
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
54
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Development of anex vivo patient-derived tumor model (PDTM) to assess the tumor microenvironment in renal cell carcinoma (RCC)
    Kashima, Soki
    Gupta, Ruchi
    Moritz, Vivien
    Sadak, Katherine
    Adeniran, Adebowale
    Humphrey, Peter
    Dinulescu, Daniel
    Palmer, Doug
    Hammond, Scott
    Bosenberg, Marcus
    Hurwitz, Michael
    Kenney, Patrick
    Braun, David
    ONCOLOGIST, 2024, 29 : S5 - S6
  • [2] Patient-derived tumor microenvironment models uncover nonautonomous TKI resistance mechanisms in NSCLC
    Hu, Haichuan
    Mulvey, Hillary
    Noeen, Sundus
    David, Kodack
    Hata, Aaron
    Niederst, Matthew
    Benes, Cyril
    Engelman, Jeffrey
    CANCER RESEARCH, 2017, 77
  • [3] Integration of Tumor Microenvironment in Patient-Derived Organoid Models Help Define Precision Medicine of Renal Cell Carcinoma
    Wang, Bingran
    Xue, Yizheng
    Zhai, Wei
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [4] Patient-derived tumor microenvironment models uncover non-autonomous TKI resistance mechanisms in NSCLC
    Hu, Haichuan
    Niederst, Matthew
    Engelman, Jeffrey
    CANCER RESEARCH, 2016, 76
  • [5] Rapid Profiling of Tumor-Immune Interaction Using Acoustically Assembled Patient-Derived Cell Clusters
    Ao, Zheng
    Wu, Zhuhao
    Cai, Hongwei
    Hu, Liya
    Li, Xiang
    Kaurich, Connor
    Chang, Jackson
    Gu, Mingxia
    Liang, Cheng
    Lu, Xin
    Guo, Feng
    ADVANCED SCIENCE, 2022, 9 (22)
  • [6] Patient-Derived Glioblastoma Explants as a Model for the Tumor Immune Microenvironment
    Shaked, Zoe
    Fernandez-Zapata, Camila
    Wasilewski, David
    Sun, Wenbo
    Bischoff, Philip
    Horst, David
    Onken, Julia Sophie
    Gholami, Mohammad Fardin
    Picht, Thomas
    Boettcher, Chotima
    Vajkoczy, Peter
    Xu, Ran
    ONCOLOGY RESEARCH AND TREATMENT, 2024, 47 : 43 - 43
  • [7] Protocol for ex vivo culture of patient-derived tumor fragments
    Roelofsen, Lisanne M.
    Voabil, Paula
    de Bruijn, Marjolein
    Herzig, Petra
    Zippelius, Alfred
    Schumacher, Ton N.
    Thommen, Daniela S.
    STAR PROTOCOLS, 2023, 4 (02):
  • [8] Patient-derived tumor explant models of tumor immune microenvironment reveal distinct and reproducible immunotherapy responses
    Turpin, Rita
    Peltonen, Karita
    Rannikko, Jenna H.
    Liu, Ruixian
    Kumari, Anita N.
    Nicorici, Daniel
    Lee, Moon Hee
    Mutka, Minna
    Kovanen, Panu E.
    Niinikoski, Laura
    Meretoja, Tuomo
    Mattson, Johanna
    Jarvinen, Petrus
    Lahdensuo, Kanerva
    Jarvinen, Riikka
    Tornberg, Sara
    Mirtti, Tuomas
    Bostrom, Pia
    Koskivuo, Ilkka
    Thotakura, Anil
    Pouwels, Jeroen
    Hollmen, Maija
    Mustjoki, Satu
    Klefstroem, Juha
    ONCOIMMUNOLOGY, 2025, 14 (01):
  • [9] Response Gene to Complement 32 is associated with poor patient survival and an inflamed tumor-immune microenvironment in clear cell renal cell carcinoma
    Li, Lingling
    Bu, Xiaocui
    Wang, Shuhui
    Liu, Yan
    Chen, Chongdao
    Zhang, Wei
    Zhao, Peng
    TRANSLATIONAL ONCOLOGY, 2025, 52
  • [10] Patient-Derived Xenograft Models in Urological Malignancies: Urothelial Cell Carcinoma and Renal Cell Carcinoma
    Tracey, Andrew T.
    Murray, Katie S.
    Coleman, Jonathan A.
    Kim, Kwanghee
    CANCERS, 2020, 12 (02)
12345