Magseed preoperative localization in non-palpable breast lesions: Our single-center Breast Unit experience

Background: This retrospective study aimed to evaluate our single-center experience with Magseed as a pre-operative localization system in a cohort of 47 patients with non-palpable breast lesions.Design and methods: Forty-seven patients with non-palpable breast lesions, who underwent Magseed pre-operative localization followed by breast-conserving surgery between November 2022 and June 2024 at our Breast Unit were enrolled in our study. The procedure involved percutaneous placement of the Magseed into the target lesion under ultrasound (66%) or stereotactic (34%) guidance. Data on patient demographics, lesion characteristics, Magseed localization and retrieval, surgical outcomes, and complications were collected and analyzed.Results: Magseed localization was successful in all cases, with no marker migration or dislodgment, and all seeds were retrieved (100%). Breast-conserving surgery was successful in 97.9% of patients, with only one requiring intraoperative widening. No significant complications were reported. Histopathology revealed predominantly invasive breast cancers, with "No Special Type" being the most common subtype (42.5%).Conclusions: The effectiveness of this technique is proven by our results, which reflect the data in the growing scientific literature on Magseed.