Advances in the Diagnosis and Management of Limbal Stem Cell Deficiency

被引：0
作者：
Kittipibul, Thanachaporn [1 ,2 ]
Dalin, Chea Piseth [3 ]
Masoudi, Ali [4 ]
Zheng, Jie [4 ]
Deng, Sophie X. [4 ,5 ]
机构：
[1] Chulalongkorn Univ, Fac Med, Ctr Excellence Cornea & Stem Cell Transplantat, Dept Ophthalmol, Bangkok, Thailand
[2] King Chulalongkorn Mem Hosp, Thai Red Cross Soc, Excellence Ctr Cornea & Stem Cell Transplantat, Dept Ophthalmol, Bangkok, Thailand
[3] Calmette Hosp, Ophthalmol Unit, Phnom Penh, Cambodia
[4] Univ Calif Los Angeles, Stein Eye Inst, David Geffen Sch Med, Dept Ophthalmol, Los Angeles, CA USA
[5] Univ Calif Los Angeles, Mol Biol Inst, Los Angeles, CA USA
来源：
CORNEA | 2025年 / 44卷 / 04期
关键词：
limbal stem cell deficiency; in vivo confocal microscopy; anterior segment optical coherence tomography; impression cytology; Wnt signaling pathway; STEM/PROGENITOR CELLS; IMPRESSION CYTOLOGY; STROMAL CELLS; KERATIN; 13; CORNEAL; TRANSPLANTATION; EPITHELIUM; EFFICIENCY; GROWTH; NICHE;
D O I：
10.1097/ICO.0000000000003775
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
This concise review focuses on the latest advancements in the diagnosis and management of limbal stem cell deficiency (LSCD). Ensuring the standard of care for individuals affected by LSCD involves the crucial task for physicians to meticulously and accurately diagnose the condition and determine its specific stage. A standardized diagnostic approach forms the foundation for formulating and delivering customized therapeutic interventions to maximize treatment outcomes for each patient. In this review, we introduce a systematic diagnostic algorithm to guide the assessment of LSCD. In addition, the current management algorithm and emerging therapies for LSCD are summarized.
引用
收藏
页码：405 / 411
页数：7
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