Comparison of short-term clinical outcomes of intra-articular injection of micro-fragmented adipose tissue and stromal vascular fraction cells for knee osteoarthritis treatment: A retrospective single- center cohort study

被引：1

作者：

Maeda, Takuma ^{[1
,2
]}

Sobajima, Satoshi ^{[2
]}

Matsumoto, Tomoyuki ^{[1
]}

Tsubosaka, Masanori ^{[1
]}

Matsushita, Takehiko ^{[1
]}

Iwaguro, Hideki ^{[2
]}

Kuroda, Ryosuke ^{[1
]}

机构：

[1] Kobe Univ, Grad Sch Med, Dept Orthopaed Surg, Kobe, Japan

[2] Sobajima Clin, Dept Orthopaed Surg, 2-2-6 Aramotokita, Higashiosaka, Osaka 5770011, Japan

来源：

REGENERATIVE THERAPY | 2025年 / 29卷

关键词：

Osteoarthritis; Knee; Adipose tissue; Stromal vascular fraction; atra-articular;

D O I：

10.1016/j.reth.2025.02.013

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Medicine. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).

引用

页码：91 / 99

页数：9

共 28 条

[1] Heterogeneous Cells as well as Adipose-Derived Stromal Cells in Stromal Vascular Fraction Contribute to Enhance Anabolic and Inhibit Catabolic Factors in Osteoarthritis [J].

Anjiki, Kensuke ;

Matsumoto, Tomoyuki ;

Kuroda, Yuichi ;

Fujita, Masahiro ;

Hayashi, Shinya ;

Nakano, Naoki ;

Tsubosaka, Masanori ;

Kamenaga, Tomoyuki ;

Takashima, Yoshinori ;

Kikuchi, Kenichi ;

Ikuta, Kenmei ;

Onoi, Yuma ;

Tachibana, Shotaro ;

Suda, Yoshihito ;

Wada, Kensuke ;

Matsushita, Takehiko ;

Kuroda, Ryosuke .

STEM CELL REVIEWS AND REPORTS, 2023, 19 (07) :2407-2419

[2] Does cartilage loss cause pain in osteoarthritis and if so, how much? [J].

Bacon, Kathryn ;

LaValley, Michael P. ;

Jafarzadeh, S. Reza ;

Felson, David .

ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 (08) :1105-1110

[3] A New Nonenzymatic Method and Device to Obtain a Fat Tissue Derivative Highly Enriched in Pericyte-Like Elements by Mild Mechanical Forces From Human Lipoaspirates [J].

Bianchi, Francesca ;

Maioli, Margherita ;

Leonardi, Erika ;

Olivi, Elena ;

Pasquinelli, Gianandrea ;

Valente, Sabrina ;

Mendez, Armando J. ;

Ricordi, Camillo ;

Raffaini, Mirco ;

Tremolada, Carlo ;

Ventura, Carlo .

CELL TRANSPLANTATION, 2013, 22 (11) :2063-2077

[4] Macrophage M1/M2 polarization [J].

Chen Yunna ;

Hu Mengru ;

Wang Lei ;

Chen Weidong .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2020, 877

[5] Regenerative Features of Adipose Tissue for Osteoarthritis Treatment in a Rabbit Model: Enzymatic Digestion Versus Mechanical Disruption [J].

Desando, Giovanna ;

Bartolotti, Isabella ;

Martini, Lucia ;

Giavaresi, Gianluca ;

Aldini, Nicolo Nicoli ;

Fini, Milena ;

Roffi, Alice ;

Perdisa, Francesco ;

Filardo, Giuseppe ;

Kon, Elizaveta ;

Grigolo, Brunella .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (11)

[6] Clinical and Radiological Comparison of Single and Double Intra-articular Injection of Adipose-Derived Stromal Vascular Fraction for Knee Osteoarthritis [J].

Fujita, Masahiro ;

Matsumoto, Tomoyuki ;

Sobajima, Satoshi ;

Tsubosaka, Masanori ;

Matsushita, Takehiko ;

Iwaguro, Hideki ;

Kuroda, Ryosuke .

CELL TRANSPLANTATION, 2023, 32

[7] Paracrine effect of the stromal vascular fraction containing M2 macrophages on human chondrocytes through the Smad2/3 signaling pathway [J].

Fujita, Masahiro ;

Matsumoto, Tomoyuki ;

Hayashi, Shinya ;

Hashimoto, Shingo ;

Nakano, Naoki ;

Maeda, Toshihisa ;

Kuroda, Yuichi ;

Takashima, Yoshinori ;

Kikuchi, Kenichi ;

Anjiki, Kensuke ;

Ikuta, Kemmei ;

Onoi, Yuma ;

Tachibana, Shotaro ;

Matsushita, Takehiko ;

Iwaguro, Hideki ;

Sobajima, Satoshi ;

Hiranaka, Takafumi ;

Kuroda, Ryosuke .

JOURNAL OF CELLULAR PHYSIOLOGY, 2022, 237 (09) :3627-3639

[8] Analyzing the Clinical Potential of Stromal Vascular Fraction: A Comprehensive Literature Review [J].

Goncharov, Evgeniy Nikolaevich ;

Koval, Oleg Aleksandrovich ;

Igorevich, Eremin Ilya ;

Ramirez, Manuel De Jesus Encarnacion ;

Nurmukhametov, Renat ;

Valentinovich, Kotenko Konstantin ;

Montemurro, Nicola .

MEDICINA-LITHUANIA, 2024, 60 (02)

[9] The role of Interleukin 1 receptor antagonist in mesenchymal stem cell-based tissue repair and regeneration [J].

Harrell, Carl Randall ;

Markovic, Bojana Simovic ;

Fellabaum, Crissy ;

Arsenijevic, Nebojsa ;

Djonov, Valentin ;

Volarevic, Vladislav .

BIOFACTORS, 2020, 46 (02) :263-275

[10] The Effect of Intra-articular Injection of Autologous Microfragmented Fat Tissue on Proteoglycan Synthesis in Patients with Knee Osteoarthritis [J].

Hudetz, Damir ;

Boric, Igor ;

Rod, Eduard ;

Jelec, Zeljko ;

Radic, Andrej ;

Vrdoljak, Trpimir ;

Skelin, Andrea ;

Lauc, Gordan ;

Trbojevic-Akmacic, Irena ;

Plecko, Mihovil ;

Polasek, Ozren ;

Primorac, Dragan .

GENES, 2017, 8 (10)

← 1 2 3 →