Dose-response effects of 8-week resistance training on body composition and muscular performance in untrained young women: A quasi-experimental design

Background:The purpose of this study was to investigate the effects of 8-week resistance training with different training volumes on body composition, maximum strength, peak power, and muscle thickness in non-training women.Methods:This was a 3-arm, prospectively designed, randomized controlled trial. A total of 45 adult women aged 20.7 +/- 1 years, the mean heights of the participants were 166 +/- 0.07 cm, body weight was measured as 54.5 +/- 8.8 kg, and body mass index was 19.9 +/- 2.1 kg/m2. They were randomized to low-volume training resistance training (LVT; n = 15, 3 sessions of 12 exercises per week), moderate-volume training resistance training (MVT; n = 15; 4 sessions of 12 exercises per week), and high-volume resistance training (HVT; n = 15; 5 sessions of 12 exercises per week) for 8 weeks. The muscle thickness (MT) of the vastus lateralis was assessed at baseline and 8 weeks later using a portable ultrasound device.Results:A total of 39 adult women completed the study, with 2 participants from each group lost to follow-up. All experimental groups 1RM increased (P = .001, effect size (ES) = 0.463) All groups showed improved muscle thickness (MT) (P = .001) and CMJ (P = .004). The group x time interaction is statistically significant (P = .001) suggests that the changes in muscle thickness over time differ significantly between the different training volume groups (eta p(2)) is 0.368.Conclusion:In untrained young women, resistance training improved muscle hypertrophy, maximal strength, power, and body composition in untrained young women. However, 4 sessions MVT per week were superior to LVT and HVT sessions, suggesting a nonlinear dose-response relationship favoring moderate volume over low or high volumes, at least in previously untrained young women.Trial Registration:ClinicalTrials.gov (NCT06449300)