Extranodal nasal-type NK/T-cell lymphoma with CD20 positive: A case report and review of literature

被引:0
作者
Han, Yongliang [1 ]
Wei, Shufei [2 ]
Zhang, Yihang [3 ]
Wang, Liangliang [2 ]
Xu, Xiao [2 ]
机构
[1] Jiujiang 1 Peoples Hosp, Dept Pathol, Jiujiang, Peoples R China
[2] Jiujiang Univ Hosp, Dept Pathol, 57 Xunyangdong Rd, Jiujiang 332000, Jiangxi, Peoples R China
[3] Jiujiang Univ Hosp, Dept Radiol, Jiujiang, Peoples R China
关键词
CD20; NK/- cell lymphoma; Nasal type; EXPRESSION;
D O I
10.4103/ijpm.ijpm_32_22
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Extranodal nasal-type natural killer (NK)/T-cell lymphoma is a type of non-Hodgkin lymphoma. Neoplastic lymphocytes are positive for CD4, CD56, and CD20, a specific B-cell marker. CD20 positive NK/T-cell lymphoma is rare, with only nine reported cases. This paper reports a case of nasal-type NK/T-cell lymphoma with CD20 positivity in a 47-year-old woman. The patient presented with bilateral nasal congestion and bloody nasal cavity secretions for 2 months. Computed tomography revealed thickening of the nasal mucosa and posterior wall of the nasopharyngeal crest, and the left and right cervical lymph nodes were enlarged. On histopathology, the lesion was composed of medium-sized atypical lymphoid cells and vascular infringement. Immunohistochemical staining showed that the tumor cells were positive for CD20, CD3, CD56, and Epstein-Barr virus (EBV)-encoded RNA in situ hybridization. The patient was treated with radiotherapy for 2 months and is currently well.
引用
收藏
页码:459 / 462
页数:4
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