Long-distance gene flow and recombination shape the evolutionary history of a maize pathogen

被引：0

作者：

Rogerio, Flavia ^{[1
,2
]}

Van Oosterhout, Cock ^{[3
]}

De Mita, Stephane ^{[4
]}

Cuevas-Fernandez, Francisco Borja ^{[1
]}

Garcia-Rodriguez, Pablo ^{[1
]}

Becerra, Sioly ^{[1
]}

Gutierrez-Sanchez, Silvia ^{[1
]}

Jacquat, Andres G. ^{[5
]}

Bettiol, Wagner ^{[6
]}

Hosaka, Guilherme Kenichi ^{[7
]}

Ulla, Sofia B. ^{[5
]}

Hiltbrunner, Juerg ^{[8
]}

Santiago, Rogelio ^{[9
]}

Revilla, Pedro ^{[9
]}

Dambolena, Jose S. ^{[5
]}

Vicente-Villardon, Jose L. ^{[10
]}

Buhinicek, Ivica ^{[11
]}

Sukno, Serenella A. ^{[1
]}

Thon, Michael R. ^{[1
]}

机构：

[1] Univ Salamanca, Inst Agribiotechnol Res CIALE, Dept MicroBiol & Genet, Salamanca 37185, Spain

[2] Univ Florida, Dept Plant Pathol, Gainesville, FL 32611 USA

[3] Univ East Anglia, Sch Environm Sci, Norwich Res Pk, Norwich, England

[4] Univ Montpellier, PHIM Plant Hlth Inst, Inst Agro, INRAE,CIRAD,IRD, Montpellier, France

[5] Natl Univ Cordoba, Fac Exact Phys & Nat Sci, IMBIV CONICET ICTA, Cordoba, Argentina

[6] Embrapa Environm, Jaguariuna, SP, Brazil

[7] Univ Sao Paulo, Luiz de Queiroz Coll Agr, Dept Genet, Lab Genet Microorganisms Prof Joao Lucio de Azeved, Piracicaba, Brazil

[8] Ctr Competences Plants & Plant Prod, Fed Dept Econ Affairs, Agroscope, Zurich, Switzerland

[9] CSIC, Mision Biol Galicia, Pontevedra, Spain

[10] Univ Salamanca, Stat Dept, Salamanca, Spain

[11] BC Inst Breeding & Prod Field Crops, Dugo Selo, Croatia

来源：

IMA FUNGUS | 2025年 / 16卷

关键词：

Colletotrichum graminicola; genetic introgression; isolation by distance (IBD); population genomics; restriction site-associated DNA sequencing (RAD-seq); whole-genome sequencing (WGS); CONIDIAL ANASTOMOSIS TUBES; PLANT-PATHOGENS; POPULATION GENOMICS; COLLETOTRICHUM; HYBRIDIZATION; REPRODUCTION; GRAMINICOLA; DISEASES; MUTATION; STRAINS;

D O I：

10.3897/imafungus.16.138888

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The evolutionary history of crop pathogens is shaped by a complex interaction of natural and anthropogenic factors. The fungus Colletotrichum graminicola causes maize anthracnose which results in significant yield losses worldwide. We conducted a comprehensive investigation into the evolutionary genomics of C. graminicola using a collection of 212 isolates from 17 countries across five continents. Genomic analyses supported the existence of three geographically isolated genetic lineages, with a significant pattern of isolation by distance. We identified two distinct gene flow patterns, driven by short- and long-distance dispersal, likely resulting from the natural spread of the pathogen and the exchange of contaminated seeds. We present evidence of genetic introgression between lineages, suggesting a long history of recombination. We identified significant recombination events coalescing at distinct points in time, with the North American lineage displaying evidence of the most ancient recombination. Demographic modelling has indicated that North America is an intermediate between Brazil, Europe and an ancestral, unsampled source population, which is hypothesised to be Mesoamerican. Our analyses revealed that the global genomic structure of C. graminicola is shaped by geographic differentiation driven by long-distance migration and a long history of recombination and introgression. We show historical relationships amongst these lineages, identifying a potential route for fungal spread, with the North American population emerging ancestrally, followed sequentially by the Brazilian and European populations. Our research indicates that the European lineage is more virulent, which has implications for the potential emergence of new outbreaks of maize anthracnose in Europe.

引用

页数：27