Diagnosis and Management of Cancers in Pregnancy: The Results of a Dual Battle Between Oncological Condition and Maternal Environment-Literature Review

被引:0
作者
Dinu, Mihai-Daniel [1 ]
Sima, Romina-Marina [2 ,3 ]
Diaconescu, Andrei-Sebastian [4 ,5 ]
Poenaru, Mircea-Octavian [2 ,3 ]
Gorecki, Gabriel-Petre [6 ,7 ]
Amza, Mihaela [1 ,3 ]
Popescu, Mihai [8 ,9 ]
Georgescu, Mihai-Teodor [4 ,10 ]
Constantin, Ancuta-Alina [11 ,12 ]
Mihai, Mara-Madalina [4 ,13 ]
Toma, Cristian-Valentin [4 ,14 ]
Ples, Liana [2 ,3 ]
机构
[1] Carol Davila Univ Med & Pharm, IOSUD Inst Offering Doctoral Studies, IOSUD, Bucharest 020021, Romania
[2] Carol Davila Univ Med & Pharm, Dept Obstet & Gynecol, Bucharest 020021, Romania
[3] St Johns Hosp, Bucur Matern, Bucharest 012361, Romania
[4] Carol Davila Univ Med & Pharm, Fac Med, Bucharest 020021, Romania
[5] Fundeni Clin Inst, Gen Surg Dept, Bucharest 022328, Romania
[6] Titu Maiorescu Univ, Fac Med, Dept Anesthesia & Intens Care, Bucharest 031593, Romania
[7] CF2 Clin Hosp, Dept Anesthesia & Intens Care, Bucharest 011464, Romania
[8] Carol Davila Univ Med & Pharm, Dept Orthoped, Bucharest 020021, Romania
[9] Bucharest Univ Emergency Hosp, 169 Splaiul Independentei, Bucharest 050098, Romania
[10] Carol Davila Univ Med & Pharm, Prof Dr Al Trestioreanu Oncol Discipline, Bucharest 020021, Romania
[11] Carol Davila Univ Med & Pharm, Dept Cardiothorac Pathol, Bucharest 020021, Romania
[12] Inst Pneumol Marius Nasta, Bucharest 050159, Romania
[13] Elias Univ, Emergency Hosp, Bucharest, Romania
[14] Spitalul Clin Prof Dr Th Burghele, Bucharest 061344, Romania
关键词
cancer; pregnancy; fetus; radiological diagnosis; nuclear medicine; chemotherapy; radiotherapy; surgery; targeted therapy; immunotherapy; breastfeeding; fertility preservation; psychological effects; SENTINEL NODE LOCALIZATION; BORDERLINE OVARIAN-TUMORS; ACUTE MYELOID-LEUKEMIA; BREAST-CANCER; MULTIDISCIPLINARY MANAGEMENT; HEMATOLOGIC MALIGNANCIES; FERTILITY PRESERVATION; GYNECOLOGIC CANCERS; RADIATION-THERAPY; INTERFERON-ALPHA;
D O I
10.3390/cancers17030389
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cancer during pregnancy presents considerable challenges that arise from various factors, including the diagnostic, prognostic and therapeutic implications of managing cancer in this unique patient population. There is a crucial need for an integrated approach that aligns medical interventions for both the pregnant patient and the developing embryo or fetus. Furthermore, the distinct characteristics associated with each stage of gestation may significantly influence the treatment protocols that can be proposed. Due to all of these factors, the importance of collaboration among healthcare professionals from different specialties (to ensure that both mother and child receive optimal care throughout the pregnancy) is often neglected. This review is designed to provide a thorough overview of the current standard procedures regarding the diagnosis and treatment options for cancer in pregnant patients in order to ensure the safety of mother and child. Furthermore, the review describes the feasibility of current fertility preservation methods, highlights the psychological effects of cancer during pregnancy and examines the risks and benefits of breastfeeding.
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页数:26
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  • [1] Dalmartello M., Negri E., La Vecchia C., Scarfone G., Buonomo B., Peccatori F.A., Parazzini F., Frequency of Pregnancy-Associated Cancer: A Systematic Review of Population-Based Studies, Cancers, 12, (2020)
  • [2] Maggen C., Wolters V.E.R.A., Cardonick E., Fumagalli M., Halaska M.J., Lok C.A.R., de Haan J., Van Tornout K., Van Calsteren K., Amant F., Et al., Pregnancy and Cancer: The INCIP Project, Curr. Oncol. Rep, 22, (2020)
  • [3] Bianchi D.W., Chudova D., Sehnert A.J., Bhatt S., Murray K., Prosen T.L., Garber J.E., Wilkins-Haug L., Vora N.L., Warsof S., Et al., Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies, JAMA, 314, pp. 162-169, (2015)
  • [4] Salani R., Billingsley C.C., Crafton S.M., Cancer and Pregnancy: An Overview for Obstetricians and Gynecologists, Am. J. Obstet. Gynecol, 211, pp. 7-14, (2014)
  • [5] Van Calsteren K., Heyns L., De Smet F., Van Eycken L., Gziri M.M., Van Gemert W., Halaska M., Vergote I., Ottevanger N., Amant F., Cancer during Pregnancy: An Analysis of 215 Patients Emphasizing the Obstetrical and the Neonatal Outcomes, J. Clin. Oncol, 28, pp. 683-689, (2010)
  • [6] Lee Y.Y., Roberts C.L., Dobbins T., Stavrou E., Black K., Morris J., Young J., Incidence and Outcomes of Pregnancy-Associated Cancer in Australia, 1994–2008: A Population-Based Linkage Study, BJOG, 119, pp. 1572-1582, (2012)
  • [7] Aktoz F., Yalcin A.C., Yuzdemir H.S., Akata D., Gultekin M., Treatment of Massive Liver Metastasis of Breast Cancer during Pregnancy: First Report of a Complete Remission with Trastuzumab and Review of Literature, J. Matern. Fetal Neonatal Med, 33, pp. 1266-1271, (2020)
  • [8] Peccatori F.A., Azim H.A., Orecchia R., Hoekstra H.J., Pavlidis N., Kesic V., Pentheroudakis G., Cancer, Pregnancy and Fertility: ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow-up, Ann. Oncol, 24, pp. Vi160-Vi170, (2013)
  • [9] Silverstein J., Post A.L., Chien A.J., Olin R., Tsai K.K., Ngo Z., Van Loon K., Multidisciplinary Management of Cancer During Pregnancy, JCO Oncol. Pract, 16, pp. 545-557, (2020)
  • [10] Amant F., Halaska M.J., Fumagalli M., Dahl Steffensen K., Lok C., Van Calsteren K., Han S.N., Mir O., Fruscio R., Uzan C., Et al., Gynecologic Cancers in Pregnancy: Guidelines of a Second International Consensus Meeting, Int. J. Gynecol. Cancer, 24, pp. 394-403, (2014)