Factors associated with unfavorable outcome of anterior circulation ischemic stroke following emergency endovascular therapy after complete recanalization

被引：0

作者：

Yang, Chunchao ^{[1
]}

Rissardo, Jamir Pitton ^{[2
]}

Caprara, Ana Leticia Fornari ^{[3
]}

Neupane, Durga ^{[4
]}

Chen, Yueming ^{[1
]}

Li, Chandi ^{[5
]}

Li, Zhenzhang ^{[6
,7
]}

Gao, Junjie ^{[5
]}

Tang, Longchong ^{[5
]}

Yu, Qingwen ^{[8
]}

Liang, Yuhang ^{[5
]}

机构：

[1] Cent Peoples Hosp Zhanjiang, Dept Emergency Med, Zhanjiang, Guangdong, Peoples R China

[2] Cooper Univ Hosp, Dept Neurol, Camden, NJ USA

[3] Univ Fed Santa Maria, Dept Med, Santa Maria, RS, Brazil

[4] BP Koirala Inst Hlth Sci, Dept Surg, Dharan, Nepal

[5] Cent Peoples Hosp Zhanjiang, Dept Neurol, Zhanjiang, Guangdong, Peoples R China

[6] Guangdong Polytech Normal Univ, Coll Math & Syst Sci, Guangzhou, Peoples R China

[7] Guangzhou Med Univ, Sch Basic Med Sci, Guangzhou, Peoples R China

[8] Cent Peoples Hosp Zhanjiang, Dept Neurosurg, Zhanjiang, Guangdong, Peoples R China

来源：

NEUROLOGY ASIA | 2024年 / 29卷 / 03期

关键词：

Recanalization; unfavorable; ischemic stroke; endovascular therapy; thrombectomy;

D O I：

10.54029/2024scr

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: Endovascular thrombectomy (EVT) improves long-term patients outcomes and decreases mortality among ischemic stroke patients. However, not all patients can benefit from EVT recanalization. The present study aims to evaluate the predictors of unfavorable outcomes associated with emergency endovascular therapy despite complete recanalization. Methods: We investigated 74 eligible patients receiving EVT from January 2019 to January 2022 at a comprehensive stroke center. Demographics, clinical, radiological and treatment characteristics, safety, and functional outcomes were collected. Modified Rankin scale (mRS) score <= 2 at 90 days was defined as a good functional outcome. Results: A total of 111 patients were initially eligible for the study, of which 37 were excluded, resulting in 74 patients in the final study. The mean age was 69.08 +/- 12.12 years old, 67.57% patients were male, 44.59% patients with atrial fibrillation, 64.86% with hypertension, 21.62% patients with diabetes mellitus, 16.22% patients with coronary artery diseases, 6.76% with parenchymal hematoma. Median 208.0 (160.0,278.5) minutes and median last known norma to puncture time (LKNPT) (IQR), was 362.0 (280, 452.5) minutes. Individuals with a poorer outcome were older [73.56 +/- 9.29 vs. 65.28 +/- 13.02 years old, P=0.002], had a higher prevalence of atrial fibrillation (AF) [58.82 vs. 13%, P=0.023] and and a slightly longer door-to-recanalization time were more prevalent in the unfavorable prognosis group; however, statistical analysis did not show any significant differences. Logistics binary regression model showed that older age [OR: 0.1.160 (1.011 to 1.112, P=0.031)] and AF [OR: 3.190 (1.111 to

引用

页码：559 / 564

页数：6

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