Cardiovascular Disease Risk Among Older Asian, Native Hawaiian, Pacific Islanders Lung Cancer Survivors

被引：0

作者：

Pan, Yancen ^{[1
,2
,3
]}

Chang, Chun-Pin Esther ^{[2
,3
]}

Tao, Randa ^{[3
,4
]}

Daud, Anees ^{[5
]}

Shen, Jincheng ^{[6
]}

Wong, Nathan D. ^{[1
,7
]}

Nianogo, Roch A. ^{[1
]}

Rao, Jianyu ^{[1
]}

Varghese, Thomas ^{[8
]}

Zhang, Zuo-Feng ^{[1
]}

Hashibe, Mia ^{[1
,2
,3
]}

机构：

[1] UCLA Fielding Sch Publ Hlth, Dept Epidemiol, Los Angeles, CA 90095 USA

[2] Univ Utah, Sch Med, Dept Family & Prevent Med, Div Publ Hlth, Salt Lake City, UT 84112 USA

[3] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[4] Univ Utah, Sch Med, Dept Radiat Oncol, Salt Lake City, UT USA

[5] Univ Utah, Sch Med, Div Cardiovasc Med, Salt Lake City, UT USA

[6] Univ Utah, Sch Med, Dept Populat Hlth Sci, Div Biostat, Salt Lake City, UT USA

[7] UCI Heart Dis Prevent Program, Div Cardiol, Irvine, CA USA

[8] Univ Utah, Sch Med, Dept Surg, Thorac Surg, Salt Lake City, UT USA

来源：

CANCER MEDICINE | 2025年 / 14卷 / 04期

关键词：

Asian; cardiovascular disease; lung cancer survivor; native Hawaiian; Pacific islander; racial disparity; ETHNIC-DIFFERENCES; DISPARITIES; HEALTH; CARDIOTOXICITY; IMPACT; STAGE; RACE;

D O I：

10.1002/cam4.70702

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

BackgroundThere may be heterogeneity in lung cancer-related outcomes for individuals who are Asian, Native Hawaiian, and Pacific Islanders (ANHPI).ObjectivesThe aims of this study were to investigate possible disparities in cardiovascular disease (CVD) risk between ANHPI and Non-Hispanic White (NHW) lung cancer survivors and evaluate potential CVD risk factors.MethodsA total of 3920 ANHPI and 11,760 NHW lung cancer patients aged 66 years and older were identified from the Surveillance, Epidemiology, and End Results (SEER)-Medicare registry from 1999 to 2017. Cox proportional hazards models were used to calculate adjusted hazard ratios (HRs) and 95% confidence intervals (95% CIs) for incident CVD, comparing ANHPI lung cancer patients and their race/ethnicity subgroups to NHW lung cancer patients.ResultsCompared to NHW lung cancer patients, ANHPI lung cancer patients had a lower risk of developing heart failure (HR, 0.64, 95% CI, 0.53-0.76) and ischemic heart disease (HR, 0.76, 95% CI, 0.60-0.95). Additionally, compared to Chinese lung cancer patients, Pacific Islander, South Asian, and Southeast Asian lung cancer patients had a higher risk of heart failure.ConclusionWhile ANHPI lung cancer patients had lower risks of heart failure and ischemic heart disease than NHW lung cancer patients, heterogeneity in risk was observed among ANHPI subgroups. Further research is needed to investigate the reasons for the higher risk of several CVDs among Pacific Islander, South Asian, and Southeast Asian lung cancer patients.

引用

页数：16

共 59 条

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