Biological activity of vanadium pincer complexes

被引：0

作者：

Delgado-Rangel, Luis Humberto ^{[1
]}

Reyes-Marquez, Viviana ^{[2
]}

Moreno-Narvaez, Maria Esther ^{[1
]}

Aragon-Muriel, Alberto ^{[3
]}

Parra-Unda, Jesus R. ^{[4
]}

Cruz-Navarro, J. Antonio ^{[1
]}

Martinez-Torres, Mayra A. ^{[1
]}

Valdes, Hugo ^{[5
]}

Morales-Morales, David ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Inst Quim, Ciudad Univ,Circuito Exterior S-N, Ciudad De Mexico 04510, Mexico

[2] Univ Sonora, Dept Ciencias Quim Biol, Luis Encinas & Rosales S-N, Hermosillo 83000, Mexico

[3] Univ Magdalena, Grp Invest Bioquim GIB, Santa Marta 470004, Colombia

[4] Univ Autonoma Sinaloa, Fac Ciencias Quim Biol, Unidad Invest Salud Publ Dra Kaethe Willms, Culiacan 80010, Mexico

[5] Univ Alcala, Fac Farm, Dept Quim Organ & Quim Inorgan, Inst Invest Quim Andres M del Rio IQAR, Alcala De Henares 28805, Madrid, Spain

来源：

NEW JOURNAL OF CHEMISTRY | 2025年 / 49卷 / 09期

关键词：

HETEROLEPTIC OXIDOVANADIUM(IV) COMPLEXES; HETEROCYCLIC CARBENE COMPLEXES; TRYPANOSOMA-CRUZI; CRYSTAL-STRUCTURE; SALICYLALDEHYDE SEMICARBAZONES; COPPER(II) COMPLEXES; POLYPYRIDYL LIGANDS; CLICK CHEMISTRY; CARBON-DIOXIDE; DNA CLEAVAGE;

D O I：

10.1039/d4nj04551c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review focuses on the biological activity of vanadium pincer complexes, exploring their applications as activators or inhibitors of enzymatic function, antioxidants, and agents with potential therapeutic effects. Specifically, their capacities as antidiabetic, antibacterial, antiviral, antiparasitic, and anticancer agents are examined in detail. The use of pincer ligands for biological applications has grown enormously in the last ten years, as these ligands can confer to the complexes they form properties such as enhanced stability, improved bioavailability, and greater specificity for pharmacological targets, potentially leading to pharmacological synergy. Additionally, the use of vanadium in the development of pharmacologically active compounds has gained attention due to its role in certain biological processes and its ability to interact with proteins by mimicking phosphorus atoms, making vanadium-containing molecules of significant interest for further study.

引用

页码：3442 / 3455

页数：14

共 50 条

[41] Synthesis, characterization, and biological activity of a fresh class of sonochemically synthesized Cu2+ complexes
Ghanbari, Hamed
Derakhshankhah, Hossein
Bahrami, Kiumars
Keshavarzi, Saeide
Mohammadi, Khosro
Hayati, Payam
Centore, Roberto
Parisi, Emmanuele
SCIENTIFIC REPORTS, 2024, 14 (01):
[42] Synthesis, structure and biological activity of nickel(II) complexes with mefenamato and nitrogen-donor ligands
Totta, Xanthippi
Papadopoulou, Aikaterini A.
Hatzidimitriou, Antonios G.
Papadopoulos, Athanasios
Psomas, George
JOURNAL OF INORGANIC BIOCHEMISTRY, 2015, 145 : 79 - 93
[43] Synthesis, spectral characterization and biological activity of metal(II) complexes with 4-aminoantipyrine derivatives
Leelavathy, C.
Antony, S. Arul
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2013, 113 : 346 - 355
[44] Synthesis, Characterization, Catalytic and Antiamoebic Activity of Vanadium Complexes of Binucleating Bis(dibasic tridentate ONS donor) Ligand Systems
Maurya, Mannar R.
Haldar, Chanchal
Khan, Aftab Alam
Azam, Amir
Salahuddin, Attar
Kumar, Amit
Pessoa, Joao Costa
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2012, (15) : 2560 - 2577
[45] Hydrolytic activity of new bioinspired MnIIIMnII and FeIIIMnII complexes as mimetics of PAPs: Biological and environmental interest
Luiz, Edinara
Farias, Giliandro
Bortoluzzi, Adailton J.
Neves, Ademir
Mattos, Larissa Maura de Melo
Pereira, Marcos Dias
Xavier, Fernando R.
Peralta, Rosely A.
JOURNAL OF INORGANIC BIOCHEMISTRY, 2022, 236
[46] Copper(II) Nitroaromatic Schiff Base Complexes: Synthesis, Biological Activity and Their Interaction with DNA and Albumins
Martins, Darliane A.
Bomfim Filho, Lucius F.
da Silva, Cleiton M.
de Fatima, Angelo
Louro, Sonia R. W.
Batista, Denise G. J.
Soeiro, Maria de Nazare C.
de Carvalho, Joao Ernesto
Teixeira, Leticia R.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2017, 28 (01) : 87 - 97
[47] Significant differences in the biological activity of mononuclear Cu(II) and Ni(II) complexes with the polyquinolinyl ligand
Li, Jun-Ling
Jiang, Lin
Wang, Bi-Wei
Tian, Jin-Lei
Gu, Wen
Liu, Xin
Yan, Shi-Ping
NEW JOURNAL OF CHEMISTRY, 2015, 39 (01) : 529 - 538
[48] Synthesis, Characterization, and Biological Activity of Transition Metal Complexes of Oxadiazole
Reddy, D. Harikishore Kumar
Harinath, Y.
Suneetha, Y.
Seshaiah, K.
Reddy, A. V. R.
SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2011, 41 (03) : 287 - 294
[49] Amido-pincer complexes of Cu(II): Synthesis, coordination chemistry and applications in catalysis
Taghvaee, Mahroo
Rodriguez-Alvarez, Maria J.
Garcia-Alvarez, Joaquin
del Rio, Ignacio
Lough, Alan J.
Gossage, Robert A.
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2017, 845 : 107 - 114
[50] The Reactivity of Mercapto Groups against Boron Hydrides in Pincer Ligated Nickel Mercapto Complexes
Zhang, Jie
Liu, Ting
Wei, Changgeng
Chang, Jiarui
Ma, Qiang-Qiang
Li, Shujun
Ma, Nana
Chen, Xuenian
CHEMISTRY-AN ASIAN JOURNAL, 2018, 13 (21) : 3231 - 3238

← 1 2 3 4 5 →